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Extremely refractory Kawasaki disease with disseminated intravascular coagulation

Published online by Cambridge University Press:  07 March 2017

Young Kwon Koh ,
Jae Hee Lee  and
Yeong Bong Park
Young Kwon Koh
Affiliation:
Department of Pediatrics, Chosun University School of Medicine, Gwangju, Republic of Korea
Jae Hee Lee
Affiliation:
Department of Pediatrics, Chosun University School of Medicine, Gwangju, Republic of Korea
Yeong Bong Park*
Affiliation:
Department of Pediatrics, Chosun University School of Medicine, Gwangju, Republic of Korea
*
Correspondence to: Y. B. Park, Department of Pediatrics, Chosun University Hospital, 365 Pilmun-daero, Dong-gu, Gwangju 61452, Republic of Korea. Tel: +82 62 220 3041; Fax: +82 62 227 2904, E-mail: [email protected]
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Abstract

Disseminated intravascular coagulation is a rare complication of Kawasaki disease and appears in <0.1% of Kawasaki disease patients. We report a case of refractory Kawasaki disease complicated with disseminated intravascular coagulation and giant coronary aneurysm. A 5-month-old boy presented with Kawasaki disease with coagulopathy. Although the coagulopathy improved after fresh-frozen plasma and antithrombin-III administration, the fever persisted despite two rounds of intravenous immunoglobulin, along with intravenous methylprednisolone pulse therapy and infliximab administration. Despite all efforts to treatment, the patient had giant coronary aneurysms and died suddenly.

Keywords

Kawasaki diseasedisseminated intravascular coagulationcoronary aneurysm
Type
Brief Report
Information
Cardiology in the Young , Volume 27 , Issue 5 , July 2017 , pp. 1004 - 1007
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Copyright
© Cambridge University Press 2017 

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