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The evaluation of arterial stiffness of essential hypertension and white coat hypertension in children: a case-control study

Published online by Cambridge University Press:  10 December 2017

Semiha Terlemez Tokgöz ,
Dilek Yılmaz ,
Yavuz Tokgöz ,
Bülent Çelik  and
Yasin Bulut
Semiha Terlemez Tokgöz*
Affiliation:
Pediatric Cardiology Department, Medicine Faculty, Adnan Menderes University, Aydın, Turkey
Dilek Yılmaz
Affiliation:
Department of Pediatric Nephrology, Adnan Menderes University, Aydın, Turkey
Yavuz Tokgöz
Affiliation:
Department of Pediatric, Adnan Menderes University, Aydın, Turkey
Bülent Çelik
Affiliation:
Faculty Statistics, Gazi University Chemistry, Ankara, Turkey
Yasin Bulut
Affiliation:
Department of Pediatric, Adnan Menderes University, Aydın, Turkey
*
Correspondence to: S. Terlemez Tokgöz, Pediatric Cardiology Department, Medicine Faculty, Adnan Menderes University, 09100 Aydın, Turkey. Tel: +90 532 721 76 89; Fax: +90 2564122573; E-mail: [email protected]
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Abstract

Background

The aim of this study was to determine and compare cardiovascular risks by assessing arterial stiffness in children with essential hypertension and white coat hypertension.

Methods

Paediatric patients followed up with essential hypertension and white coat hypertension diagnoses and with no established end organ damage were involved in the study. Arterial stiffness in children included in the study was evaluated and compared by using the oscillometric device (Mobil-O-Graph) method.

Results

A total of 62 essential hypertension (34 male, 28 female), 38 white coat hypertension (21 male, 17 female), and 60 healthy controls (33 male, 27 female) were assessed in the present study. Pulse wave velocity of the essential hypertension, white coat hypertension, and control group was, respectively, as follows: 5.3±0.6 (m/s), 5.1±0.4 (m/s), 4.3±0.4 (m/s) (p<0.001); augmentation index outcomes were, respectively, determined as follows: 21.3±6.5, 19.3±6.4, 16.0±0.3 (p<0.001). Pulse wave velocity and augmentation index values of children with essential hypertension and white coat hypertension were found to be higher compared with the control group. This level was identified as correlated with the duration of hypertension in both patient groups (p<0.01).

Conclusion

Arterial stiffness in children with essential hypertension and white coat hypertension was impaired compared with healthy children. This finding has made us think that white coat hypertension is not an innocent clinical situation. This information should be taken into consideration in the follow-up and treatment approaches of the patients.

Keywords

Essential hypertensionwhite coat hypertensionarterial stiffness
Type
Original Articles
Information
Cardiology in the Young , Volume 28 , Issue 3 , March 2018 , pp. 403 - 408
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Copyright
© Cambridge University Press 2017 

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