Hostname: page-component-586b7cd67f-tf8b9 Total loading time: 0 Render date: 2024-11-23T00:36:19.487Z Has data issue: false hasContentIssue false
  • English
  • Français

Dengue disease in a pediatric patient with severe idiopathic pulmonary hypertension

Published online by Cambridge University Press:  14 December 2020

Gabriel Díaz Open the ORCID record for Gabriel Díaz [Opens in a new window] ,
Claudia P. Devia  and
Orlando M. De La Hoz
Gabriel Díaz*
Affiliation:
Pediatric Cardiologist, Titular Professor, Department of Pediatrics, Universidad Nacional de Colombia, Fundación Santa Fe de Bogota, Bogota, Colombia
Claudia P. Devia
Affiliation:
Fellow of Neonatology, Universidad Nacional de Colombia, Bogota, Colombia
Orlando M. De La Hoz
Affiliation:
Fellow of Pediatrics, Universidad Nacional de Colombia, Bogota, Colombia
*
Author for correspondence: Gabriel Díaz, MD, Titular Professor, Department of Pediatrics, Universidad Nacional de Colombia, Fundación Santa Fe de Bogotá, Carrera 9 No 116-20 Of. 332; Bogota, Colombia. Tel: 57-3158791259. E-mail: [email protected]; [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Dengue virus can affect the heart, with complications as bradycardia, arrhythmias, and death. We present a case of a 15-year-old patient, diagnosed 4 years before with severe idiopathic pulmonary hypertension, confirmed by catheterism, with continuous follow up. At that time, she was living in Bogotá (2640 m above sea level). Sildenafil and Macitentan were started. She was recommended to live at low altitude and she moved. The patient was transferred back to Bogota, from that place, due to flu-like symptoms and fever. Immunoglobulin M for dengue was confirmed and second-degree atrioventricular block Mobitz I with bradycardia (40 beats/minute) was documented throughout the clinical course. She recovered.

Keywords

Dengue diseaseheart AV blockarrhythmiasidiopathic pulmonary hypertensionhigh altitude pulmonary hypertension
Type
Brief Report
Information
Cardiology in the Young , Volume 31 , Issue 4 , April 2021 , pp. 654 - 657
Check for updates
Copyright
© The Author(s), 2020. Published by Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Díaz Góngora, GF. Hipertensión pulmonar a moderada altura en niños. Rev Colomb Cardiol 2012; 19: 199–207.Google Scholar
Penaloza, D, Sime, F and Ruiz, L. Pulmonary hemodynamics in children living at high altitudes. High Altitude Medicine & Biology 2008; 9: 199–207.CrossRefGoogle ScholarPubMed
Ministerio de la Protección Social -OPS/OMS. Guía para la atención clínica integral del paciente con dengue. Bogotá, 2010. https://www.minsalud.gov.co.Google Scholar
Yacoub, S, Wertheim, H, Cameron, P, et al. Cardiovascular manifestations of the emerging dengue pandemic. Nat Rev Cardiol 2014; 11: 335–345.CrossRefGoogle ScholarPubMed
Lammers, AE, Adatia, I, Del Cerro, MJD, Diaz, G, Freudenthal, AH, Freudenthal, F, et al. A functional classification of pulmonary hypertension in children: report from the PVRI pediatric taskforce, Panama 2011. Pulm Circ 2011; 1: 280–285.CrossRefGoogle ScholarPubMed
Yantie, NP, Gunawijaya, E, Suradipa, I, Gustawan, I. Asymptomatic cardiadc rythm abnormality in children with dengue virus infection. Bali Med J 2016; 5: 351–354.CrossRefGoogle Scholar
Harpreet, S, Gagan Sukhija, D, Bala, S, et al. Second degree Mobitz type 1 block in dengue haemorrhagic fever: a rare manifestation. J Clin Diagn Res 2018; 12: OD04–OD05.Google Scholar
Rajarethinam, J, Ang, LW, Ong, J, et al. Dengue in Singapore from 2004 to 2016: cyclical epidemic patterns dominated by serotypes 1 and 2. Am J Trop Med Hyg 2018; 99: 204–210.CrossRefGoogle ScholarPubMed
Tisoncik, JR, Korth, MJ, Simmons, CP, et al. Into the eye of the cytokine storm. microbiology and molecular biology reviews. MMBR 2012; 76: 16–32.CrossRefGoogle Scholar
Bhamarapravati, N, Tuchinda, P, Boonyapaknavik, V. Pathology of Thailand haemorrhagic fever: a study of 100 autopsy cases. Ann Trop Med Parasitol 1967; 61: 500–510.CrossRefGoogle ScholarPubMed
Kularatne, SA, Pathirage, MMK, Kumarasiri, PVR, et al. Cardiac complications of a dengue fever outbreak in Sri Lanka, 2005. Trans R Soc Trop Med and Hygiene 2007; 101: 804–808.CrossRefGoogle ScholarPubMed