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Comparison of trace element levels after cardiopulmonary bypass between cyanotic and acyanotic patients

Published online by Cambridge University Press:  07 February 2018

Firat H. Altin ,
Bahar Ozturk Kurt ,
Ibrahim C. Tanidir ,
Mehmet Kaya ,
Okan Yildiz ,
Meliha Z. Kahraman ,
Sinem B. Celebi ,
Erkut Ozturk  and
Semra Ozdemir
Firat H. Altin*
Affiliation:
Department of Pediatric Cardiovascular Surgery, Istanbul Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey
Bahar Ozturk Kurt
Affiliation:
Department of Biophysics, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
Ibrahim C. Tanidir
Affiliation:
Department of Pediatric Cardiology, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey
Mehmet Kaya
Affiliation:
Department of Pediatric Cardiovascular Surgery, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey
Okan Yildiz
Affiliation:
Department of Pediatric Cardiovascular Surgery, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey
Meliha Z. Kahraman
Affiliation:
Department of Anesthesiology and Reanimation, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey
Sinem B. Celebi
Affiliation:
Department of Anesthesiology and Reanimation, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey
Erkut Ozturk
Affiliation:
Department of Pediatric Cardiology, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey
Semra Ozdemir
Affiliation:
Department of Biophysics, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
*
Author for correspondence: F. H. Altin, MD, Istanbul Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Selimiye Neighborhood, Tibbiye Street. No:13, Uskudar, 34668 Istanbul, Turkey. Tel: +90 533 241 16 39; Fax: +90 212 414 30 69; E-mail: [email protected]
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Abstract

Trace elements are essential micronutrients for the human body. In this study, we evaluated the alterations in copper, chromium, manganese, selenium, magnesium, zinc, iron, arsenic, boron, and silicon levels in children with cyanotic and acyanotic CHD who underwent cardiac surgery with cardiopulmonary bypass. Participants were divided into the following three groups: patients acyanotic CHDs (n=34), patients with cyanotic CHDs (n=30), and healthy controls (n=30). Blood samples were collected before the surgery and 1 hour after the sternum was closed. Serum trace elements were determined by Inductively Coupled Plasma Optical Emission Spectrometer-ICAP 6000. The baseline serum arsenic, manganese, and zinc levels of both patient groups were lower compared with controls, but there was no significant difference between baseline serum trace element levels of cyanotic and acyanotic patients. In both the patient groups, there was a significant decrease in postoperative serum arsenic, boron, copper, and zinc levels, and a significant increase in postoperative serum iron and magnesium levels. Silicon levels increased in cyanotic patients. Alterations in trace element levels were in the same direction in cyanotic and acyanotic patients. Copper, zinc, and manganase replacement may be needed after on-pump cardiac surgery.

Keywords

Trace elementcardiac surgerycardiopulmonary bypasscyanoticacyanotic
Type
Original Articles
Information
Cardiology in the Young , Volume 28 , Issue 5 , May 2018 , pp. 632 - 638
Copyright
© Cambridge University Press 2018 

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Footnotes

*

This study was presented in the 9th Istanbul Symposium on 24 November 2015.

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