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Clinical and electrophysiological characteristics, and relatively benign outcome, of typical atrioventricular nodal reentrant tachycardia in children and adolescents

Published online by Cambridge University Press:  18 August 2008

Alfredo Di Pino*
Affiliation:
Paediatric Cardiology, S. Vincenzo Hospital, Taormina, Italy
Elio Caruso
Affiliation:
Paediatric Cardiology, S. Vincenzo Hospital, Taormina, Italy
Dario Salvo
Affiliation:
Paediatric Cardiology, S. Vincenzo Hospital, Taormina, Italy
Innocenzo Bianca
Affiliation:
Paediatric Cardiology, S. Vincenzo Hospital, Taormina, Italy
*
Correspondence to: Alfredo Di Pino, Unità Operativa di Cardiologia Pediatrica, Ospedale S. Vincenzo Contrada Sirina, 98039 Taormina Messina, Italy. Tel: 0942579550; Fax: 094252215; E-mail: [email protected]

Abstract

Background

Atrioventricular nodal re-entrant tachycardia is an uncommon arrhythmia in children. The natural history of this disturbance is poorly known in young patients.

Methods

We analyzed the clinical and electrophysiological features, and the final outcome, in 19 children affected by typical atrioventricular nodal re-entrant tachycardia diagnosed by a transoesophageal electrophysiological study.

Results

Of the cohort, 12 patients were female and 7 male, with a mean age of 11 years. Dual atrioventricular nodal physiology was demonstrated in 14 children (73%). The mean length of the tachycardia cycle was 297 milliseconds, with periods of 2 to 1 atrioventricular block during tachycardia noted in 5 children (26%). The mean cycle length was significantly shorter in the children who presented episodes of 2 to 1 atrioventricular block than in those who did not. After diagnosis, 12 children were not treated, 6 were treated with medical therapy, and 1 was submitted to radiofrequency transcatheter ablation. During a mean follow-up period of 41 months, 2 children with rare, but sustained, episodes of tachycardia that initially had not been treated were submitted to radiofrequency transcatheter ablation. Among children treated pharmacologically, 1 teenager was submitted to radiofrequency transcatheter ablation on the basis of parental choice, 3 children have discontinued medical therapy recording only sporadic episodes of tachycardia, and 2 children are still treated with antiarrhythmic drugs. At the last follow-up visit, 13 children (68%) were without any treatment, 4 had been successfully ablated, and 2 were still on medical treatment.

Conclusions

Our data indicates a relatively benign outcome in this group of children and adolescents with atrioventricular nodal re-entrant tachycardia.

Type
Original Article
Copyright
Copyright © Cambridge University Press 2008

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References

1. Ko, JK, Deal, B, Strasburger, J, Benson, DW Jr. Supraventricular tachycardia mechanism and their age distribution in paediatric patients. Am J Cardiol 1992; 69: 10281032.CrossRefGoogle Scholar
2. Crosson, JE, Hesslein, PS, Thilenius, OG, Dunnigan, A. AV node reentry tachycardia in infants. Pacing Clin Electrophysiol 1995; 18: 21442149.Google Scholar
3. Gross, G, Epstein, MR, Walsh, EP, Saul, P. Characteristics, management and midterm outcome in infants with atrioventricular nodal reentry tacxhycardia. Am J Cardiol 1998; 82: 956960.CrossRefGoogle Scholar
4. Josephson, ME, Kastor, JA. Supraventricular tachycardia: mechanisms and management. Ann Inter Med 1977; 87: 346358.Google Scholar
5. Brembilla-Perrot, B, Marcon, F, Bosser, G, et al. Paroxysmal tachycardia in children and teenagers with normal sinus rhythm and without heart disease. Pacing Clin Electrophysiol 2001; 24: 4145.Google Scholar
6. ACC/AHA/ESC Guidelines for the management of patients with supraventricular arrhythmias. A Report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for the management of Patients with Supraventricular Arrhythmias). J Am Coll Cardiol 2003; 15 42: 14931531.Google Scholar
7. Friedman, RA, Walsh, EP, Silka, MJ, et al. NASPE expert consensus conference: radiofrequency catheter ablation in children with and without congenital heart disease. Report of the writing committee. Pacing Clin Electrophysiol 2002; 23: 19161920.Google Scholar
8. Benson, DW, Dunnigan, A, Benditt, DG, Pritzker, MR, Thompson, TR. Transesophageal study of infant supraventricular tachycardia. Electrophysiologic characteristics. Am J Cardiol 1983; 52: 10021006.CrossRefGoogle ScholarPubMed
9. Schaffer, SM, Gillette, PC. Ventriculoatrial intervals during narrow complex re-entrant tachycardia in children. Am Heart J 1991; 121: 16991702.CrossRefGoogle Scholar
10. Drago, F, Grutter, G, Silvetti, MS, De Santis, A, Di Ciommo, V. Atrioventricular nodal reentrant tachicardia in children. Pediatr Cardiol 2006; 27: 454459.CrossRefGoogle Scholar
11. Bertram, H, Windhagen-Mahnert, B, Bokenkamp, R, et al. Abbreviated combined anatomical/electrophysiological approach for catheter ablation of atrioventricular nodal re-entrant tachycardia in children. Cardiol Young 2001; 11: 182187.CrossRefGoogle ScholarPubMed
12. Otto, H, Teixeira, P, Seshadri, B, Case, CL, Gillette, P. Radiofrequency catheter ablation of atrioventricular nodal reentrant tachycardia in children. Pacing Clin Electrophysiol 1994; 17: 16211626.Google Scholar
13. Silka, MJ, Halperin, BD, Hardy, BG, McAnulty, JH, Kron, J. Safety and efficacy of radiofrequency transcatheter modification of slow pathway conduction in children <10 years of age with atrioventricular node re-entrant tachycardia. Am J Cardiol 1997; 80: 13641367.Google Scholar
14. Anderson, JL, Platt, ML, Guarnieri, T, Fox, TL, Maser, MJ, Pritchett, EL, on behalf of the Flecainide Supraventricular tachycardia Study Group. Flecainide acetate for paroxysmal supraventricular tachyarrhythmias. Am J Cardiol 1994; 74: 578584.Google Scholar
15. Henthorn, RW, Waldo, AL, Anderson, JL, et al. . on behalf of the Flecainide Supraventricular Tachycardia Study Group. Flecainide acetate prevents recurrences of symptomatic supraventricular tachycardia. Circulation 1991; 83: 119125.Google Scholar
16. Niazi, I, Naccarelli, G, Dougherty, A, Rinkenberger, R, Tchou, P, Akhtar, M. Treatment of atrioventricular node re-entrant tachycardia with encainide: reversal of drug effect with isoproterenol. J Am Coll Cardiol 1989; 13: 904916.CrossRefGoogle Scholar
17. Bexton, RS, Hellestrand, KJ, Nathan, AW, Spurrell, RA, Camm, AJ. A comparison of the antiarrhythmia effect on AV junctional re-entrant tachycardia of oral and intravenous flecainide acetate. Eur Heart J 1983; 4: 92102.Google Scholar
18. Akhtar, M, Jazayeri, MR, Sra, J, Blanck, Z, Deshpande, S, Dhala, A. Atrioventricular nodal reentry. Clinical electrophysiological, and therapeutic considerations. Circulation 1993; 88: 282295.CrossRefGoogle ScholarPubMed
19. Mehta, AV, Chidambaram, B. Efficacy and safety of intravenous and oral nadolol for supraventricular tachycardia in children. J Am Coll Cardiol 1992; 19: 636637.Google Scholar
20. Van Hare, GF, Chiesa, NA, Campbell, RM, Kanter, RJ, Cecchin, F. Atrioventricular nodal re-entrant tachycardia in children: Effect of slow pathway ablation on fast pathway function. J Cardiovasc Electrophysiol 2002; 13: 203209.CrossRefGoogle ScholarPubMed
21. Samson, RA, Deal, BJ, Strasburger, JF, Benson, DW. Comparison of transesophageal and intracardiac electrophysiologic studies in characterization of supraventricular tachycardia in paediatric patients. J Am Coll Cardiol 1995; 26: 159163.Google Scholar
22. Man, KC, Brinkman, K, Bogun, F, et al. 2:1 atrioventricular block during atrioventricular nodal re-entrant tachycardia. J Am Coll Cardiol 1996; 28: 17701774.Google Scholar
23. Lee, SH, Tai, CT, Chiang, CE, et al. Spontaneous transition of 2:1 atrioventricular block to 1:1 atrioventricular conduction during atrioventricular nodal re-entrant tachycardia: evidence supporting the intra-Hisian or infra-Hisian area as the site of block. J Cardiovasc Electrophysiol 2003; 14: 13371341.Google Scholar
24. Cohen, MI, Wieand, TS, Rhodes, LA, Vetter, VL. Electrophysiologic properties of the atrioventricular node in pediatric patients. J Am Coll Cardiol 1997; 29: 403407.CrossRefGoogle ScholarPubMed
25. Blaufox, AD, Rhodes, JF, Fishberger, SB. Age related changes in dual AV nodal physiology. Pacing Clin Electrophysiol 2000; 23: 477480.Google Scholar
26. Lee, PC, Chen, SA, Chiang, CE, Tai, CT, Yu, WC, Hwang, B. Clinical and electrophysiological characteristics in children with atrioventricular nodal re-entrant tachycardia. Pediatr Cardiol 2003; 24: 69.Google Scholar
27. Blaufox, AD, Saul, JP. Influences on fast and slow pathway conduction in children: does the definition of dual atrioventricular node physiology need to be changed? J Cardiovasc Electrophysiol 2002; 13: 210211.CrossRefGoogle ScholarPubMed
28. Natale, A, Klein, G, Yee, R, Thakur, R. Shortening of fast pathway refractoriness after slow pathway ablation. Effect of autonomic blockade. Circulation 1994; 89: 11031108.Google Scholar
29. Musto, B, Cavallaro, C, Musto, A, D’ Onofrio, A, Belli, A, De Vincentis, L. Flecainide single oral dose for management of paroxsismal supraventricular tachicardia in children and young adults. Am Heart J 1992; 124: 110115.Google Scholar
30. Alboni, P, Tomasi, C, Menozzi, C, et al. Efficacy and safety of out-of-Hospital self-administerd single dose oral drug treatment in the management of infrequent, well-tolerated paroxysmal supraventricular tachycardia. J Am Coll Cardiol 2001; 37: 548553.Google Scholar
31. Avari, JN, Jay, KS, Rhee, EK. Experience and results during transition from radiofrequency ablation to cryoablation for treatment of pediatric atrioventricular nodal re-entrant tachycardia. Pacing Clin Electrophysiol 2008; 31: 454460.CrossRefGoogle Scholar
32. Perry, JC, Garson, AJ. Supraventricular tachycardia due to Wolff-Parkinson-White syndrome in children: early disappearance and late recurrence. J Am Coll Cardiol 1990; 16: 12151220.Google Scholar
33. Vignati, G, Balla, E, Mauri, L, Lunati, M, Figini, A. Clinical and electrophysiologic evolution of the Wolff-Parkinson-White syndrome in children: impact on approaches to management. Cardiol Young 2000; 10: 367375.Google Scholar
34. Clair, WK, Wilkinson, WE, Mc Carthy, EA, Page, RL, Prichett, ELC. Spontaneous occurrence of symptomatic paroxysmal atrial fibrillation and paroxysmal supraventricular tachycardia in untreated patients. Circulation 1993; 87: 11141122.CrossRefGoogle ScholarPubMed
35. Chen, SA, Chiang, CE, Tai, CT, et al. Longitudinal clinical and electrophysiological assessment of patients with symptomatic Wolff-Parkinson-White syndrome and atrioventricular node reentrant tachycardia. Circulation 1996; 93: 20232032.Google Scholar