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Cerebral perfusion and metabolism after profound hypothermia—comparison between procedures involving no flow and low flow

Published online by Cambridge University Press:  19 August 2008

Rolf Ekroth ,
Jan van der Linden ,
Christopher Lincoln  and
Michael Scallan
Rolf Ekroth
Affiliation:
From the Departments of Thoracic and Cardiovascular Surgery
Jan van der Linden
Affiliation:
Anesthesia and Intensive Care
Christopher Lincoln*
Affiliation:
Sahlgrenska Hospital, Gothenburg, and the Departments of Cardiothoracic Surgery
Michael Scallan
Affiliation:
Anaesthesia, Royal Brompton National Heart & Lung Hospital, London
*
Mr. Christopher Lincoln, Department of Cardiothoracic Surgery, Royal Brompton National Heart and Lung Hospital, Sydney Street, London SW3 6NP, United Kingdom.
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Extract

The debate concerning no flow versus low flow continues. Thus, it has not yet been possible to conclude whether limited period of total circulatory arrest, as opposed to maintained but reduced systemic flow, offers superior protection of the brain during cardiac surgery in children. While most previous work has focused on the hypothermic period of no versus low flow, less is known about the conditions during and after rewarming with full systemic flow. Some previous data, which related the ischemic marker creatine kinase BB during profound hypothermic procedures, suggested that neural dysfunction was aggravated by posthypothermic factors such as hyperglycemia, acidosis and anemia.

Keywords

Pediatric anesthesiabrain blood flowbrain metabolismcardiac surgery
Type
World Forum for Pediatric Cardiology Symposium on Cardiopulmonary Bypass (Part 2)
Information
Cardiology in the Young , Volume 3 , Issue 4 , October 1993 , pp. 378 - 382
Copyright
Copyright © Cambridge University Press 1993

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References

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