Hostname: page-component-586b7cd67f-g8jcs Total loading time: 0 Render date: 2024-11-23T12:23:07.906Z Has data issue: false hasContentIssue false
  • English
  • Français

Aortic root aneurysm repair in a neonate with Loeys–Dietz syndrome

Part of: Surgery

Published online by Cambridge University Press:  25 January 2021

Willa Li Open the ORCID record for Willa Li [Opens in a new window] ,
William Cohen ,
Pamela Combs ,
Joshua Wong Open the ORCID record for Joshua Wong [Opens in a new window] ,
Rohit Loomba ,
Brian K. Lee ,
Chawki El-Zein ,
Michel Ilbawi ,
Luca Vricella  and
Narutoshi Hibino
Willa Li
Affiliation:
Section of Cardiac Surgery, Department of Surgery, The University of Chicago, Chicago, IL, USA
William Cohen
Affiliation:
Section of Cardiac Surgery, Department of Surgery, The University of Chicago, Chicago, IL, USA
Pamela Combs
Affiliation:
Section of Cardiac Surgery, Department of Surgery, The University of Chicago, Chicago, IL, USA
Joshua Wong
Affiliation:
Pediatric Cardiology, Advocate Children’s Heart Institute, Advocate Children’s Hospital, Oak Lawn, IL, USA
Rohit Loomba
Affiliation:
Pediatric Cardiology, Advocate Children’s Heart Institute, Advocate Children’s Hospital, Oak Lawn, IL, USA
Brian K. Lee
Affiliation:
Pediatric Cardiology, Advocate Children’s Heart Institute, Advocate Children’s Hospital, Oak Lawn, IL, USA
Chawki El-Zein
Affiliation:
Pediatric Cardiac Surgery, Advocate Children’s Heart Institute, Advocate Children’s Hospital, Oak Lawn, IL, USA
Michel Ilbawi
Affiliation:
Pediatric Cardiac Surgery, Advocate Children’s Heart Institute, Advocate Children’s Hospital, Oak Lawn, IL, USA
Luca Vricella
Affiliation:
Section of Cardiac Surgery, Department of Surgery, The University of Chicago, Chicago, IL, USA Pediatric Cardiac Surgery, Advocate Children’s Heart Institute, Advocate Children’s Hospital, Oak Lawn, IL, USA
Narutoshi Hibino*
Affiliation:
Section of Cardiac Surgery, Department of Surgery, The University of Chicago, Chicago, IL, USA Pediatric Cardiac Surgery, Advocate Children’s Heart Institute, Advocate Children’s Hospital, Oak Lawn, IL, USA
*
Author for correspondence: Dr N. Hibino, MD, PhD, Section of Cardiac Surgery, Department of Surgery, The University of Chicago, 5841 S. Maryland, Rm E-500, MC5040, Chicago, IL60637, USA. Tel: 773-834-3707; Fax: 773-702-4187. E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Loeys–Dietz syndrome is a connective tissue disorder known to cause aggressive aortopathy in paediatric patients, but it is extremely rare for cardiovascular events to present during infancy. We report the first successful aortic repair in a neonate with LDS presenting in extremis with an early onset, massive aortic aneurysm.

Keywords

Loeys–Dietz syndromeneonateaortic root aneurysm
Type
Brief Report
Information
Cardiology in the Young , Volume 31 , Issue 5 , May 2021 , pp. 848 - 850
Check for updates
Copyright
© The Author(s), 2021. Published by Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Patel, ND, Alejo, D, Crawford, T, et al. Aortic root replacement for children with Loeys-Dietz syndrome. Ann Thorac Surg 2017; 103: 1513–1518.CrossRefGoogle ScholarPubMed
Cleuziou, J, Eichinger, WB, Schreiber, C, Lange, R. Aortic root replacement with re-implantation technique in an infant with Loeys-Dietz syndrome and a bicuspid aortic valve. Pediatr Cardiol 2010; 31: 117–119.CrossRefGoogle Scholar
Liu, RH, Fraser, CD 3rd, Zhou, X, Cameron, DE, Vricella, LA, Hibino, N. Pseudoaneurysm formation after valve sparing root replacement in children with Loeys-Dietz syndrome. J Card Surg 2018; 33: 339–343.CrossRefGoogle ScholarPubMed
Everitt, MD, Pinto, N, Hawkins, JA, Mitchell, MB, Kouretas, PC, Yetman, AT. Cardiovascular surgery in children with Marfan syndrome or Loeys-Dietz syndrome. J Thorac Cardiovasc Surg 2009; 137: 1327–1332.CrossRefGoogle ScholarPubMed
Williams, JA, Loeys, BL, Nwakanma, LU, et al. Early surgical experience with Loeys-Dietz: a new syndrome of aggressive thoracic aortic aneurysm disease. Ann Thorac Surg 2007; 83: S757–S763.CrossRefGoogle ScholarPubMed
Jacques, F, Grosse-Wortmann, L, Hickey, EJ, Chitayat, D, Van Arsdell, GS, Bradley, TJ. Unexpected contained rupture of a ductus arteriosus aneurysm found at surgical repair in an infant with Loeys-Dietz syndrome. Ann Thorac Surg 2013; 95: 710–711.CrossRefGoogle Scholar
Wisniewski, K, Singer, S, Kehl, HG, Nawrocki, P, Januszewska, K, Malec, E. Valve-sparing aortic root replacement in an 8-month-old infant with Loeys-Dietz syndrome. Ann Thorac Surg 2019; 107: e321–e323.CrossRefGoogle Scholar