Hostname: page-component-cd9895bd7-gbm5v Total loading time: 0 Render date: 2024-12-25T02:25:35.108Z Has data issue: false hasContentIssue false
  • English
  • Français

Advanced pulmonary vascular disease: the Eisenmenger syndrome

Published online by Cambridge University Press:  14 October 2009

R. Krishna Kumar  and
Julio Sandoval
R. Krishna Kumar*
Affiliation:
Amrita Institute of Medical Sciences and Research Center, Cochin, Kerala, India and
Julio Sandoval
Affiliation:
Cardiopulmonary Department National Institute of Cardiology “Ignacio Chávez”, Mexico City, Mexico
*
Correspondence to: R. Krishna Kumar, MD, DM, FACC, FAHA, Department of Pediatric Cardiology, Amrita Institute of Medical Sciences, Cochin, Kerala, 682026, India. Tel: 00 91 484 285 1599; Fax: 00 91 484 280 2020; E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'

Keywords

Pulmonary hypertensioncongenital heart diseasecongenital heart disease in adults
Type
Continuing Medical Education
Information
Cardiology in the Young , Volume 19 , Issue 6 , December 2009 , pp. 622 - 626
Copyright
Copyright © Cambridge University Press 2009

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Eisenmenger, V. Die angeborenen Defecte der Kammerssheidewand des Herzens. Z Klin Med 1897; 32 (Suppl 1): 1–28.Google Scholar
2.Wood, P. The Eisenmenger syndrome or pulmonary hypertension with reversed central shunt. Br Med J 1958; 2: 755–762.CrossRefGoogle ScholarPubMed
3.Granton, JT, Rabinovitch, M. Pulmonary arterial hypertension in congenital heart disease. Cardiol Clin 2002; 20: 441–457.CrossRefGoogle ScholarPubMed
4.Celermajer, DS, Cullen, S, Deanfield, DE. Impairment of endothelium- dependent pulmonary artery relaxation with congenital heart disease and abnormal pulmonary hemodynamics. Circulation 1993; 87: 440–446.CrossRefGoogle ScholarPubMed
5.Diller, GP, Gatzoulis, MA. Pulmonary vascular disease in adults with congenital heart disease. Circulation 2007; 115: 1039–1050.CrossRefGoogle ScholarPubMed
6.Perloff, JK, Rosove, MH, Sietsema, KE, Territo, MC. Cyanotic congenital heart disease: A multisystem disorder. In: Perloff JK, Child JS (eds). Congenital Heart Disease in Adults. WB Saunders Company. A division of Harcourt Brace & Company, Philadelphia, Penn, 1988, pp 199–226.Google Scholar
7.Broberg, CS, Uebing, A, Cuomo, L, Thein, SL, Papdopoulous, MG, Gatzoulis, MA. Adult patients with Eisenmenger syndrome report flying safely on commercial airlines. Heart 2007; 93: 1599–1603; originally published online 12 Dec 2006.CrossRefGoogle ScholarPubMed
8.Penalosa, D, Arias-Stella, J. The Heart and Pulmonary Circulation at High Altitudes: Healthy Highlanders and Chronic Mountain Sickness. Circulation 2007; 115: 1132–1146.CrossRefGoogle Scholar
9.Yentis, SM, Steer, PJ, Plaat, F. Eisenmenger’s syndrome in pregnancy: maternal and fetal mortality in the 1990s. Br J Obstet Gynaecol 1998; 105: 921–922.CrossRefGoogle ScholarPubMed
10.Lovell, AT. Anaesthetic implications of grown-up congenital heart disease. Br J Anaesth 2004; 93: 129–139.CrossRefGoogle ScholarPubMed
11.Perloff, JK, Marelli, AJ, Miner, PD. Risk of stroke in adults with cyanotic congenital heart disease. Circulation 1993; 87: 1954–1959.CrossRefGoogle ScholarPubMed
12.Perloff, JK, Rosove, MH, Child, JS, Wright, GB. Adults with cyanotic congenital heart disease: hematologic management. Ann Int Med 1988; 109: 406–413.CrossRefGoogle ScholarPubMed
13.Broberg, CS, Bax, BE, Okonko, DO, et al. Blood viscosity and its relationship to iron deficiency, symptoms, and exercise capacity in adults with cyanotic congenital heart disease. J Am Coll Cardiol 2006; 48: 356–365.CrossRefGoogle ScholarPubMed
14.Broberg, C, Ujita, M, Babu-Narayan, S, et al. Massive pulmonary artery thrombosis with haemoptysis in adults with Eisenmenger’s syndrome: a clinical dilemma. Heart 2004; 90: e63.CrossRefGoogle ScholarPubMed
15.Broberg, CS, Ujita, M, Prasad, S, et al. Pulmonary arterial thrombosis in Eisenmenger syndrome is associated with biventricular dysfunction and decreased pulmonary blood velocity. J Am Coll Cardiol 2007; 50: 634–642.CrossRefGoogle Scholar
16.Bowyer, JJ, Busst, CM, Denison, DM, Shinebourne, EA. Effect of long term oxygen treatment at home in children with pulmonary vascular disease. Br Heart J 1986; 55: 385–390.CrossRefGoogle ScholarPubMed
17.Sandoval, J, Aguirre, JS, Pulido, T, et al. Nocturnal oxygen therapy in patients with the Eisenmenger syndrome. Am J Respir Crit Care Med 2001; 164: 1682–1687.CrossRefGoogle ScholarPubMed
18.Galie, N, Beghetti, M, Gatzoulis, MA, et al. Bosentan Randomized Trial of Endothelial Antagonist Therapy-5 (BREATHE-5) Investigators. Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study. Circulation 2006; 114: 48–54.CrossRefGoogle Scholar
19.Apostolopoulou, SC, Manginas, A, Cokkinos, DV, Rammos, S. Long-term oral bosentan treatment in patients with pulmonary arterial hypertension related to congenital heart disease: a 2-year study. Heart 2007; 93: 350–354.CrossRefGoogle ScholarPubMed
20.Galie, N, Ghofrani, HA, Torbicki, A, et al. Sildenafil citrate therapy for pulmonary arterial hypertension. N Engl J Med 2005; 353: 2148–2157.CrossRefGoogle ScholarPubMed
21.Mukhopadhyay, S, Sharma, M, Ramakrishnan, S, et al. Phosphodiesterase-5 Inhibitor in Eisenmenger Syndrome: A Preliminary observational study. Circulation 2006; 114: 1807–1810.CrossRefGoogle ScholarPubMed
22.Diller, GP, Dimopoulos, K, Broberg, CS, et al. Presentation, survival prospects, and predictors of death in Eisenmenger syndrome: a combined retrospective and case-control study. Eur Heart J 2006; 27: 1737–1742.CrossRefGoogle ScholarPubMed
23.Hopkins, WE, Ochoa, LL, Richardson, GW, Trulock, EP. Comparison of the hemodynamics and survival of adults with severe primary pulmonary hypertension or Eisenmenger syndrome. J Heart Lung Transplant 1996; 15: 100–105.Google ScholarPubMed
24.Adriaenssens, T, Delcroix, M, Van Deyk, K, Budts, W. Advanced therapy may delay the need for transplantation in patients with the Eisenmenger syndrome. Eur Heart J 2006; 27: 1472–1477.CrossRefGoogle ScholarPubMed