Hostname: page-component-586b7cd67f-t7fkt Total loading time: 0 Render date: 2024-11-26T12:14:32.228Z Has data issue: false hasContentIssue false
  • English
  • Français

Acute intraprocedural thrombosis during an arterial ductal stenting successfully managed by eptifibatide

Part of: Interventional Cardiology

Published online by Cambridge University Press:  31 August 2021

Zeeshan Ahmed Mumtaz Open the ORCID record for Zeeshan Ahmed Mumtaz [Opens in a new window]  and
Kothandam Sivakumar Open the ORCID record for Kothandam Sivakumar [Opens in a new window]
Zeeshan Ahmed Mumtaz
Affiliation:
Department of Pediatric Cardiology, Institute of Cardio Vascular Diseases, Madras Medical Mission, Chennai, India
Kothandam Sivakumar*
Affiliation:
Department of Pediatric Cardiology, Institute of Cardio Vascular Diseases, Madras Medical Mission, Chennai, India
*
Author for correspondence: Dr K. Sivakumar, MD, DM, Head of Department of Pediatric Cardiology, Institute of Cardio Vascular Diseases, Madras Medical Mission, 4A, Dr J J Nagar, Mogappair, Chennai600037, India. Tel: +91 944444 49966; Fax: +914426565859. E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Acute stent thrombosis may complicate neonatal arterial duct stenting for reduced pulmonary blood flow. Thrombolytic agents recanalise the clot but may cause bleeding around the vascular sheaths and other sites. Since early thrombus is platelet mediated, intravenous platelet glycoprotein inhibitor like eptifibatide is likely to be effective, but rarely utilised in neonates. Ductal stent thrombosis treated with eptifibatide is reported.

Keywords

Plateletsglycoprotein receptorspatent arterial ductductal stentthrombosisocclusion
Type
Brief Report
Information
Cardiology in the Young , Volume 32 , Issue 4 , April 2022 , pp. 665 - 667
Check for updates
Copyright
© The Author(s), 2021. Published by Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Sagar, P, Sivakumar, K, Umamaheshwar, KL, et al. Are early palliative procedures providing an adequate long-term benefit in young cyanotic infants from developing countries, despite advances in surgery and interventions? Cardiol Young 2021; 31: 358–370.CrossRefGoogle ScholarPubMed
Promphan, W, Qureshi, S. Technical modifications for ductal stenting in neonates with duct-dependent pulmonary circulation. Hearts 2021; 2: 188–201.CrossRefGoogle Scholar
Kirtane, A, Stone, G. How to minimize stent thrombosis. Circulation 2011; 124: 1283–1287.CrossRefGoogle ScholarPubMed
Emani, S, Pereira, LM, Piekarski, BL, et al. Platelet inhibition with IV glycoprotein IIb/IIIa inhibitor to prevent thrombosis in pediatric patients undergoing aortopulmonary shunting. Pediatr Crit Care Med 2020; 21: e354–e361.CrossRefGoogle ScholarPubMed
Emani, S, Kaza, AK, Almodovar, M, et al. Intravenous GPIIb/IIIa inhibitor for secondary prevention of shunt thrombosis in a pediatric patient. Ann Thorac Surg 2015; 99: e151–e153.CrossRefGoogle ScholarPubMed
Mack, EH, Wheeler, DS, Hirsch, R. Endovascular treatment of near-fatal neonatal superior vena cava syndrome. Pediatr Crit Care Med 2011; 12: e410–e412.CrossRefGoogle ScholarPubMed
Bhatt, M, Anil, SR, Sivakumar, K, et al. Neonatal Kawasaki disease. Indian J Pediatr 2004; 71: 353–354.10.1007/BF02724106CrossRefGoogle ScholarPubMed
Alwi, M. Stenting the ductus arteriosus: case selection, technique and possible complications. Ann Pediatr Cardiol 2008; 1: 38–45.CrossRefGoogle ScholarPubMed
Batchelor, WB, Tolleson, TR, Huang, Y, et al. Randomized COMparison of platelet inhibition with abciximab, tirofiban and eptifibatide during percutaneous coronary intervention in acute coronary syndromes: the COMPARE trial. Circulation 2002; 106: 1470–1476.CrossRefGoogle ScholarPubMed
Giugliano, RP, White, JA, Bode, C, et al. Early versus delayed, provisional eptifibatide in acute coronary syndromes. N Engl J Med 2009; 360: 2176–2190.CrossRefGoogle ScholarPubMed

Mumtaz and Sivakumar supplementary material

Mumtaz and Sivakumar supplementary material 1

Download Mumtaz and Sivakumar supplementary material(Video)
Video 979.8 KB

Mumtaz and Sivakumar supplementary material

Mumtaz and Sivakumar supplementary material 2

Download Mumtaz and Sivakumar supplementary material(Video)
Video 1 MB