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Transient severe isolated right ventricular hypertrophy in neonates

Published online by Cambridge University Press:  24 May 2005

Munesh Tomar ,
Sitaraman Radhakrishnan  and
Savitri Shrivastava
Munesh Tomar
Affiliation:
Escorts Heart Institute and Research Centre, Department of Pediatric Cardiology, New Delhi, India
Sitaraman Radhakrishnan
Affiliation:
Escorts Heart Institute and Research Centre, Department of Pediatric Cardiology, New Delhi, India
Savitri Shrivastava
Affiliation:
Escorts Heart Institute and Research Centre, Department of Pediatric Cardiology, New Delhi, India
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Abstract

We report two instances of transient isolated right-sided myocardial hypertrophy in patients with an intact ventricular septum, normal thickness of the posterior wall of the left ventricle, and normal ventricular function, diagnosed by echocardiography on the third day of life. The two neonates, born at 36 and 38 weeks gestation respectively, had perinatal distress. Both were diagnosed as having isolated right ventricular hypertrophy with mild pulmonary hypertension, which disappeared in both cases within 8 weeks without any specific therapy. Though the cause of the ventricular hypertrophy remains unclear, we believe that it is the consequence of remodeling of pulmonary vasculature secondary to acute perinatal distress, resulting in persistent pulmonary hypertension and producing pressure overload on the right ventricle, and hence right ventricular hypertrophy. The finding of early and transient right ventricular hypertrophy, with normal left-sided structures and normal ventricular function, has thus far failed to gain attention in the paediatric cardiologic literature.

Keywords

Isolated right ventricular hypertrophyperinatal distresscongenital cardiac diseaseneonates
Type
Brief Report
Information
Cardiology in the Young , Volume 13 , Issue 4 , August 2003 , pp. 384 - 386
Copyright
© 2003 Cambridge University Press

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