Hostname: page-component-cd9895bd7-jkksz Total loading time: 0 Render date: 2024-12-24T01:22:38.498Z Has data issue: false hasContentIssue false

Successful treatment of a thrombus in the left aortic coronary sinus in a child with systemic lupus erythematosus

Published online by Cambridge University Press:  23 October 2009

Stanimir Georgiev*
Affiliation:
Department of Pediatric Cardiology, National Heart Hospital, Sofia, Bulgaria
Alexandra Lacheva
Affiliation:
Department of Pediatric Cardiology, National Heart Hospital, Sofia, Bulgaria
Maya Pavlova
Affiliation:
Department of Pediatric Cardiology, National Heart Hospital, Sofia, Bulgaria
*
Correspondence to: Stanimir Georgiev, National Heart Hospital, Konjovitsa str. 65, 1309 Sofia, Bulgaria. Tel.: +359 888 53 54 86; E-mail: [email protected]

Abstract

We report our experience in a 12 year old boy referred with suspected myocardial infarction. He has previously been diagnosed with systemic lupus erythematosus, and was being treated with steroids. Echocardiographic examination revealed a thrombus in the left aortic coronary sinus of Valsalva partially occluding the orifice of the left coronary artery. The thrombosis was successfully treated by venous thrombolysis using recombinant tissue plasminogen activator.

Type
Brief Reports
Copyright
Copyright © Cambridge University Press 2009

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Romero-Diaz, J, Garcia-Sosa, I, Sanchez-Guerrero, J. Thrombosis in systemic lupus erythematosus and other autoimmune diseases of recent onset. J Rheumatol 2009; 36 (1): 6875.Google Scholar
2.Ito, H, Takahashi, K, Sasaki, H, et al. Large thrombus in the ascending aorta successfully treated by thrombolysis – an unusual cause of acute massive myocardial infarction. Jpn Circ J 2001; 65 (6): 572574.Google Scholar
3.Dik, H, Hellemans, I. An unusual cause of myocardial infarction? Eur Heart J 1993; 14 (3): 428430.CrossRefGoogle ScholarPubMed
4.Bertrand, O, Trahan, S, Rodés-Cabau, J, et al. Appending thrombus on ulceration of the ascending aorta: A rare cause of acute ST-elevation myocardial infarction. Circulation 2009; 119 (9): e227e229.Google Scholar
5.Avcin, T, Cimaz, R, Silverman, ED, et al. Pediatric antiphospholipid syndrome: clinical and immunologic features of 121 patients in an international registry. Pediatrics 2008; 122 (5): e1100e1107.Google Scholar
6.Silver, A, Shao, C, Ginzler, E. Aortitis and aortic thrombus in systemic lupus erythematosus. Lupus 2006; 15 (8): 541543.Google Scholar
7.Manco-Johnson, M, Grabowski, E, Hellgreen, N, et al. Recommendations for tPA thrombolysis in children. On behalf of the Scientific Subcommittee on Perinatal and Pediatric Thrombosis of the Scientific and Standardization Committee of the International Society of Thrombosis and Haemostasis. Thromb Haemost 2002; 88 (1): 157158.CrossRefGoogle Scholar