Hostname: page-component-586b7cd67f-t7czq Total loading time: 0 Render date: 2024-11-26T10:13:38.533Z Has data issue: false hasContentIssue false
  • English
  • Français

Retrospective study of neonatal ligation during 2002 in the United Kingdom of persistently patent arterial ducts

Published online by Cambridge University Press:  01 August 2009

Vidheya Venkatesh ,
Lleona Lee ,
Deborah White  and
Wilf Kelsall
Vidheya Venkatesh
Affiliation:
The Neonatal Unit, Addenbrookes Hospital, Cambridge, United Kingdom
Lleona Lee
Affiliation:
Neonatal Intensive Care Unit, North Staffordshire NHS Trust, Stoke on Trent, United Kingdom
Deborah White
Affiliation:
The Neonatal Unit, Addenbrookes Hospital, Cambridge, United Kingdom
Wilf Kelsall*
Affiliation:
The Neonatal Unit, Addenbrookes Hospital, Cambridge, United Kingdom
*
Correspondence to: Dr. Wilf Kelsall, Consultant Neonatalogist, Neonatal Intensive Care Unit, Box 226, Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 2QQ, United Kingdom. Tel: 01223 216240; Fax: 01223 217064; E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Our aim was to ascertain the number of neonatal ligations of the patent arterial duct performed in the United Kingdom in 2002, and to determine the survival of the neonates after 30 days. A postal questionnaire was sent to the lead paediatician in every hospital in the United Kingdom possessing a special care or neonatal intensive care unit, requesting information on the number of babies referred for ligation of a persistently patent arterial duct. A separate questionnaire was sent to the paediatric cardiothoracic centres for information on babies who underwent the procedure. Cross-referencing the responses identified neonates who were not reported in the separate questionnaires. Additional information was requested from the central cardiac audit database. The overall response rate was 74%, with 172 forms returned of 234 distributed. From the combined responses, we ascertained that ligation has been performed in 244, with survival at 30 days of 94%. There were problems in identifying some babies because of the incomplete nature of the information received from both referring hospitals and specialist cardiothoracic centres. We would recommend a joint prospective study is conducted by paediatricians and paediatric cardiologists to determine the short and long term outcomes in this population known to be at high risk.

Keywords

Pretermcardiothoracic centrespaediatricians
Type
Original Articles
Information
Cardiology in the Young , Volume 19 , Issue 4 , August 2009 , pp. 383 - 388
Copyright
Copyright © Cambridge University Press 2009

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Dollberg, S, Lusky, A, Reichman, B. Patent ductus arteriosus, indomethacin and necrotizing enterocolitis in very low birth weight infants: a population based study. J Pediatr Gastroenterol Nutr 2005; 40: 184–188.Google ScholarPubMed
2.Marshall, DD, Kotelchuck, M, Young, ET, et al. Risk factors for chronic lung disease in the surfactant era: a North Carolina population based study of very low birth weight infants. Pediatrics 1999; 104: 1345–1350.CrossRefGoogle Scholar
3.Raval, MV, Laughon, MM, Bose, CL, Phillips, JD. Patent ductus arteriosus in premature infants: who really benefits, and at what cost? J Pediatr Surg 2007; 42: 69–75.CrossRefGoogle ScholarPubMed
4.Lee, L, Yates, R, Tillet, A, Kelsall, W. Outcome following patent ductus arteriosus ligation in premature infants: a retrospective cohort analysis. BMC Pediatr 2006; 6: 15–20.CrossRefGoogle ScholarPubMed
5.Brooks, JM, Travadi, JN, Patole, SK, Doherty, DA, Simmer, K. Is surgical ligation of patent ductus arteriosus necessary? The Western Australian experience of conservative management. Arch Dis Child Fetal Neonatal Ed 2005; 90: F235–F239.CrossRefGoogle ScholarPubMed
6.Kabra, N, Schmidt, B, Roberts, R, et al. Neurosensory impairment after surgical closure of patent ductus arteriosus in extremely low birth weight infants: results from the trial of indomethacin prophylaxis in preterms. J Pediatr 2007; 150: 229–234.CrossRefGoogle ScholarPubMed
7.Chorne, N, Leonard, C, Piecuch, R, Clyman, R. Patent ductus arteriosus and its treatment as risk factors for neonatal and neurodevelopmental morbidity. Pediatrics 2007; 119: 1165–1174.CrossRefGoogle ScholarPubMed