Hostname: page-component-586b7cd67f-t7czq Total loading time: 0 Render date: 2024-11-23T05:34:05.466Z Has data issue: false hasContentIssue false

Progression of congenital aortic stenosis in children beyond infancy: assessment using Doppler echocardiography

Published online by Cambridge University Press:  19 August 2008

Punit Goel
Affiliation:
Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India
Krishan Kumar
Affiliation:
Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India
S.S. Kothari
Affiliation:
Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India
Anita Saxena*
Affiliation:
Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India
Harbans S. Wasir
Affiliation:
Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India
*
Dr Anita Saxena, Associate Professor, Department of Cardiology, All India Institute of Medical SciencesNew Delhi 110029. India. Tel 91-11-6864851, 661123, Fax 91-11-6862663

Abstract

Case records of 67 children who presented beyond infancy (57 male, 10 female) with congenital valvar aortic stenosis were reviewed to assess progression utilizing the Doppler derived peak gradient as the index of severity. Age at presentation ranged from 1–13 years, and mean follow-up was 67 ± 29 months (range 12–142 months). The patients were divided into three groups depending on the rate of progression. Those with the most rapid rate of progression were significantly older when aortic stenosis was detected and at the time of presentation compared to the other two groups, who progressed minimally or not at all (p < 0.002 and p < 0.01 respectively). There was no significant correlation between the progression of stenosis and other clinical or Doppler echocardiographic variables.

Type
Original Articles
Copyright
Copyright © Cambridge University Press 1997

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Wagner, HR, Ellison, RC, Keane, JF, Humphries, JV, Nadas, AS. Clinical course in aortic stenosis. Circulation 1977; 56: Suppl I4756.Google Scholar
2.Cohen, LS, Friedman, WF, Braunwald, E. Natural history of mild congenital aortic stenosis elucidated by serial hemodynamic studies. Am J Cardiol 1972; 30: 15.Google Scholar
3.El, Said G, Galioto, FM, Mullins, CE, McNamara, DG. Natural hemodynamic history of congenital aortic stenosis in childhood. Am J Cardiol 1972; 30: 612.Google Scholar
4.Currie, PJ, Seward, JB, Reeder, GS, et al. Continuous wave doppler echocardiographic assessment of severity of calcific aortic stenosis: a simultaneous Doppler catheter correlative study in 100 patients. Circulation 1985; 71: 11621169.Google Scholar
5.Otco, CM, Pearlman, AS, Gardner, CL. Hemodynamic progression of aortic stenosis in adults assessed by doppler echocardiography. J Am Coll Cardiol 1989; 13: 545550.Google Scholar
6.Roger, VL, Tajik, AJ, Bailey, KR, Oh, JK, Taylor, KL, Seward, JB. Progression of aortic stenosis in adults: new appraisal using doppler echocardiography. Am Heart J 1990; 119: 331338.Google Scholar
7.Faggiano, P, Ghizzoni, G, Sorgato, A, et al. Rate of progression of valvular aortic stenosis in adults. Am J Cardio 1992; 70: 229233.Google Scholar
8.Ciobanu, M, Abbasi, AS, Allen, M, Spellberg, RD, Hermer, A. Doppler Echocardiography in the evaluation of severity of aortic insufficency. Circulation, 1980; 62: 111251 (abstr.).Google Scholar
9.Hoffman, JIE. The natural history of congenital isolated pulmonic and aortic stenosis. Ann Rev Med 1969; 20: 1528.Google Scholar
10.Wagner, S, Selzer, A. Patterns of Progression of aortic stenosis: A longitudinal hemodynamic study. Circulation 1982; 65: 709712.Google Scholar