Hostname: page-component-586b7cd67f-vdxz6 Total loading time: 0 Render date: 2024-11-26T04:07:20.407Z Has data issue: false hasContentIssue false

Pharmacologic therapy with flecainide for asymptomatic Wolff–Parkinson–White syndrome in an infant with severe left ventricular dyssynchrony

Published online by Cambridge University Press:  31 May 2018

Sayo Suzuki*
Affiliation:
Department of Pediatric Cardiology, Yokohama City University Hospital, Fukuura 3-9, Kanazawa-ku, Yokohama city, Kanagawa 236-0004, Japan
Tatsunori Hokosaki
Affiliation:
Department of Pediatric Cardiology, Yokohama City University Hospital, Fukuura 3-9, Kanazawa-ku, Yokohama city, Kanagawa 236-0004, Japan
Mari Iwamoto
Affiliation:
Department of Pediatric Cardiology, Yokohama City University Hospital, Fukuura 3-9, Kanazawa-ku, Yokohama city, Kanagawa 236-0004, Japan
*
Author for correspondence: S. Suzuki. Department of Pediatric Cardiology, Yokohama City University Hospital, Fukuura 3-9, Kanazawa-ku, Yokohama city, Kanagawa 236-0004, Japan. Tel: +81 45 787 2800, E-mail: [email protected]

Abstract

Some asymptomatic patients with Wolff–Parkinson–White syndrome have severe left ventricular dyssynchrony and dysfunction. We describe a patient who was given a diagnosis of Wolff–Parkinson–White syndrome in infancy and had a complete response to pharmacologic therapy with flecainide. Our findings suggest that flecainide is a suitable resynchronisation therapy for such infants.

Type
Brief Report
Copyright
© Cambridge University Press 2018 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Tomaske, M, Janousek, J, Razek, V, et al. Adverse effects of Wolff-Parkinson-White syndrome with right septal or posteroseptal accessory pathways on cardiac function. Europace 2008; 10: 1811892.Google Scholar
2. Kwon, BS, Bae, EJ, Kim, GB, et al. Septal dyskinesia and global left ventricular dysfunction in pediatric Wolff-Parkinson-White syndrome with septal accessory pathway. J Cardiovasc Electrophysiol 2010; 21: 290295.Google Scholar
3. Kwon, E, Carter, K, Carter, J, et al. Radiofrequency catheter ablation for dyssynchrony-induced dilated cardiomyopathy in an infant. Congenit Heart Dis 2014; 9: E179E184.Google Scholar
4. Cadrin-Tourigny, J, Fournier, A, Andelfinger, G, et al. Severe left ventricular dysfunction in infants with ventricular preexcitation. Heart Rhythm 2008; 5: 13201322.Google Scholar
5. Peach, C, Flosdorff, P, Gebauer, RA, et al. Pharmacologic cardiac resynchronization of 1-year-old boy with severe left ventricular dysfunction. Pediatr Cardiol 2012; 33: 12131215.Google Scholar
6. Friedman, RA, Walsh, EP, Silka, MJ, et al. NAPSE Expert Consensus Conference: radiofrequency catheter ablation in children with and without congenital heart disease: report of the writing committee. North American Society of Pacing and Electrophysiology. Pacing Clin Electrophysiol 2002; 25: 10001017.Google Scholar
7. Suzuki, Y, Suzuki, T, Inuzuka, R, et al. An infant with heart failure due to ventricular dyssynchrony and refractory tachycardia caused by a right anterolateral accessory pathway. Cardiology 2012; 123: 108112.Google Scholar
8. Kim, SH, Jeong, SI, Huh, J, et al. Amiodarone and catheter ablation as cardiac resynchronization therapy for children with dilated cardiomyopathy and Wolff-Parkinson-White syndrome. Korean Circ J 2013; 43: 5761.Google Scholar
9. Fazio, G, Mongiovi, M, Sutera, L, et al. Segmental dyskinesia in Wolff–Parkinson–White syndrome: A possible cause of dilative cardiomyopathy. Int J Cardiol 2008; 123: e31e34.Google Scholar
10. Bosser, G, Marcon, F, Lethor, JP, et al. Long-term efficacy and tolerability of amiodarone in children. Arch Mal Coeur Vaiss 1995; 88: 731736.Google Scholar