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Pattern of symptomatic congenital heart disease among oriental neonates—a decade's experience

Published online by Cambridge University Press:  19 August 2008

Maurice P. Leung ,
T. C. Yung ,
Y. K. Ng ,
K. Y. Wong ,
S. L. Lee ,
C. K. Mok ,
Jan Lee  and
Clement Chiu
Maurice P. Leung*
Affiliation:
From the Department of Paediatrics, Grantham Hospital, University of Hong Kong, Hong Kong
T. C. Yung
Affiliation:
From the Department of Paediatrics, Grantham Hospital, University of Hong Kong, Hong Kong
Y. K. Ng
Affiliation:
From the Department of Paediatrics, Grantham Hospital, University of Hong Kong, Hong Kong
K. Y. Wong
Affiliation:
From the Department of Paediatrics, Grantham Hospital, University of Hong Kong, Hong Kong
S. L. Lee
Affiliation:
From the Department of Paediatrics, Grantham Hospital, University of Hong Kong, Hong Kong
C. K. Mok
Affiliation:
From the Department of Surgery, Grantham Hospital, University of Hong Kong, Hong Kong
Jan Lee
Affiliation:
From the Department of Surgery, Grantham Hospital, University of Hong Kong, Hong Kong
Clement Chiu
Affiliation:
From the Department of Surgery, Grantham Hospital, University of Hong Kong, Hong Kong
*
Dr. Maurice P. Leung, Paediatric Cardiological Division, University of Hong Kong, Grantham Hospital, 125 Wong Chuk Hang Road, Aberdeen, Hong Kong. Tel. (852) 25182629; Fax. (852) 25539491.
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Abstract

Between 1981 and 1990, 765 symptomatic neonates with major congenital heart malformations were admitted into the Grantham Hospital. This represented an incidence of 10 per 10,000 live births for Hong Kong. The figure was comparable to those reported for Caucasians. Among the 744 Oriental neonates, obstruction of the pulmonary outflow tract occurred most frequently (281, 37.8%), followed by left ventricular outflow tract obstruction (169, 22.7%), left-to-right shunting (115, 15.5%), complete transposition (92, 12.4%), common mixing situations (62,8.3%), and miscellaneous causes (25, 3.3%). When compared with the available reports from the West, Chinese neonates had a high preference for pulmonary outflow tract obstruction (p<0.005), especially the anomaly of pulmonary atresia and intact ventricular septum. This correlated well with cyanosis as the commonest neonatal presentation (64%). Contrary to previous reports that aortic coarctation was rare among Orientals, this abnormality was observed frequently in our study. The rare occurrence of critical aortic valvar stenosis among Chinese, however, was supported by our present analysis. Other lesions, such as left-to-right shunting and complete transposition, showed no significant racial difference in the frequency of occurrence. Such knowledge concerning the pattern of congenital heart disease amongst Oriental neonates can facilitate early diagnosis and timely referral of babies to the appropriate center for management.

Keywords

Neonatecongenital heart disease
Type
Original Manuscripts
Information
Cardiology in the Young , Volume 6 , Issue 4 , October 1996 , pp. 291 - 297
Copyright
Copyright © Cambridge University Press 1996

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