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Orthotopic heart transplantation in patient with Williams syndrome: case report and considerations in perioperative and long-term management

Published online by Cambridge University Press:  24 January 2025

Alee N. Pettit Open the ORCID record for Alee N. Pettit [Opens in a new window] ,
Lindsay J. Nitsche ,
Humera Ahmed ,
Michael Catalano  and
Constantine D. Mavroudis
Alee N. Pettit*
Affiliation:
Drexel University College of Medicine, Philadelphia, PA, USA
Lindsay J. Nitsche
Affiliation:
Division of Cardiothoracic Surgery, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
Humera Ahmed
Affiliation:
Division of Cardiology, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
Michael Catalano
Affiliation:
Division of Cardiothoracic Surgery, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
Constantine D. Mavroudis
Affiliation:
Division of Cardiothoracic Surgery, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
*
Corresponding author: Alee N. Pettit; Email: [email protected]
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Abstract

This report describes the first long-term survival following a heart transplant for Williams syndrome-associated cardiac pathologies. An 11-year-old patient with severe global left ventricular dysfunction presented with heart failure and underwent heart transplantation. Her peri- and post-operative courses were complicated by hypertension related to underlying vascular pathology.

Keywords

Williams syndromecongenital cardiologyorthotopic heart transplantation
Type
Brief Report
Information
Cardiology in the Young , Volume 35 , Issue 1 , January 2025 , pp. 212 - 213
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Copyright
© The Author(s), 2025. Published by Cambridge University Press

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References

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