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Novice experience with transcatheter closure of the arterial duct in children, adolescents and adults
Published online by Cambridge University Press: 19 August 2008
Abstract
Non-surgical occlusion of the arterial duct (ductus arteriosus) has been shown to be effective. Its limitations are yet to be fully defined. We have attempted to elucidate this issue in the setting of our early experience with the procedure, utilizing the Rashkind double disc occluder. After clinical and echocardiographic evaluation, 56 consecutive patients were studied invasively. In two patients, the patent duct was considered too large for occlusion and in one patient it could not be crossed with the diagnostic catheter. In the remaining 53 patients (95%), an attempt to implant the double disc occluder was made. The mean age of all patients was 7.9 years (range 0.16 year to 29 years). There were 35 females (63%) and 21 males. The mean weight was 24.2 kg (range 6.7 kg–85 kg). In five patients (9.5%), the procedure failed. This was due to pull through of the 17 mm device in three patients. In another patient, because of a very small duct (post surgical ligation), it was not possible to deliver the distal legs of the 12mm device. In the last patient, the device embolized to the left pulmonary artery and was retrieved to the groin. Subsequent replacement was not attempted. In 48/53 patients (90.5%) the device was successfully implanted. Nine cases of the 48 in whom the device was implanted (18.8%) showed complete occlusion at 10 minutes and 22 more (45.8%) five to 24 hours after the procedure. A total of3 1/48 patients (64.5%) were discharged home the day following the procedure with no residual shunt, as judged by color flow Doppler studies. The mean duration of the procedure in all patients was 94 minutes (range 47 to 244). The fluoroscopy time ranged from 3 to 81 minutes with a mean of 17 minutes. Follow-up data (between five days and 18 months) are available in 20/48 patients. Three patients had a clinically detectable residual shunt, with an audible continuous murmur six months after the procedure. All three have undergone complete occlusion using a second device. One more patient showed spontaneous occlusion on follow-up. So far, a total of 35/48 patients (72.9%) have had complete occlusion of the patent duct. We conclude that not all patients with an arterial duct are amenable to occlusion using the Rashkind device. The procedure appears to be safe when performed by a suitably trained novice, nonetheless, and successful implantation can be achieved in over 90% of patients.
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