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Nitric oxide given via a head-box for persistent neonatal pulmonary hypertension

Published online by Cambridge University Press:  19 August 2008

Paul H. Martin
Affiliation:
From the Cardiac Intensive Care, Royal Liverpool Children's Hospital, Liverpool
Narayanswami Sreeram
Affiliation:
From the Cardiac Intensive Care, Royal Liverpool Children's Hospital, Liverpool
Andy J. Petros*
Affiliation:
From the Cardiac Intensive Care, Royal Liverpool Children's Hospital, Liverpool
*
Dr. A. J. Petros, Cardiac Intensive Care, Royal Liverpool Children's Hospital, Liverpool L12 2AP, United Kingdom, Tel. 44-51-228-4811.

Abstract

A neonate presenting with persistent pulmonary hypertension and severe hypoxemia was treated with nitric oxide administered into a head-box. Improvement of clinical, biochemical and echocardiographic parameters were observed during therapy, suggesting an acute decrease of pulmonary arterial pressure. It is feasible to administer nitric oxide to non-ventilated neonates provided all recommended safety precautions are observed

Type
Brief Reports
Copyright
Copyright © Cambridge University Press 1995

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References

Petros, AJ, Cox, PB, Bohn, D.Simple method for monitoring concentration ofinhaled nitric oxide. Lancet 1992; 340: 1167.CrossRefGoogle ScholarPubMed
Frostell, C, Fratacci, M-D, Wain, JC, Jones, R, Zapol, WM.Inhaled nitric oxide: a selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction. Circulation; 1991: 83: 20382047.CrossRefGoogle ScholarPubMed
Abman, SH, Chatfield, BA, Hall, SL, McMurtry, IF.Role of EDRF during transition of pulmonary circulation at birth. Am J Physiol 1990; 259: H1921H1927.Google ScholarPubMed
Roberts, JD, Lang, P, Bigatello, LM, Vlahakes, GJ, Zapol, WM.Inhaled nitric oxide in congenital heart disease. Circulation 1993; 87: 447453.CrossRefGoogle ScholarPubMed
Roberts, JD, Polaner, DM, Lang, P, Zapol, WM.Inhaled nitric oxide in persistent pulmonary hypertension of the newborn. Lancet 1992; 340: 818819.CrossRefGoogle ScholarPubMed
Kinsella, JP, Neish, SR, Shaffer, E, Abmans, SH.Low-dose inhalational nitric oxide in persistent pulmonary hypertension of the newborn. Lancet 1992; 340: 819820.CrossRefGoogle ScholarPubMed