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Long on QT and low on calcium

Published online by Cambridge University Press:  21 January 2005

Timothy J. Bradley
Affiliation:
Division of Cardiology, The Hospital for Sick Children, Toronto, Canada
Daniel L. Metzger
Affiliation:
Division of Endocrinology, British Columbia's Children's Hospital, Vancouver, Canada
Shubhayan Sanatani
Affiliation:
Division of Cardiology, British Columbia's Children's Hospital, Vancouver, Canada

Abstract

Acquired lengthening of the QT interval due to hypocalcaemia is a rare cause of arrhythmia in childhood. Early recognition, rapid institution of appropriate cardiac monitoring, and replacement therapy are essential. An endocrinal work-up may be necessary to exclude primary disorders of calcium metabolism. We report four cases documenting the varied clinical spectrum in which hypocalcaemic-induced prolongation of the QT interval and arrhythmia can occur in childhood.

Type
Brief Report
Copyright
© 2004 Cambridge University Press

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References

Surawicz B. Relationship between electrocardiogram and electrolytes. Am Heart J 1967; 73: 814834.Google Scholar
Hoffman JI. The prolonged QT syndrome. Adv Pediatr 2001; 48: 115156.Google Scholar
Viskin S. Long QT syndromes and torsade de pointes. Lancet 1999; 354: 16251633.Google Scholar
Roden DM. A practical approach to torsade de pointes. Clin Cardiol 1997; 20: 285290.Google Scholar
Trippel DL, Parsons MK, Gillette PC. Infants with long-QT syndrome and 2:1 atrioventricular block. Am Heart J 1995; 130: 11301134.Google Scholar
Phillips JR, Case CL, Gillette PC. Atrioventricular block in a newborn with acquired long QT syndrome. Cardiol Young 2001; 11: 680682.Google Scholar
Buzi F, Badolato R, Mazza C, et al. Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy syndrome: time to review diagnostic criteria? J Clin Endocrinol Metab 2003; 88: 31463148.Google Scholar
Akiyama T, Batchelder J, Worsman J, Moses HW, Jedlinski M. Hypocalcemic Torsades de Pointes. J Electrocardiol 1989; 22: 8992.Google Scholar
Huang TC, Cecchin FC, Mahoney P, Portman MA. Corrected QT interval (QTc) prolongation and syncope associated with pseudohypoparathyroidism and hypocalcemia. J Pediatr 2000; 136: 404407.Google Scholar