Article contents
Kawasaki disease shock syndrome in the COVID-19 pandemic
Published online by Cambridge University Press: 19 July 2021
Abstract
Multisystem inflammatory syndrome in children is a new entity in association with SARS-CoV2. Clinical features of Kawasaki disease were noted from the first reported cases of MIS-C. Before the COVID-19 pandemic, Kawasaki disease shock syndrome was considered to be a distinct and unique form of KD. We present a representative case that prove the current difficulty in clearly distinguishing MIS-C from pre-COVID-19-KDSS and emphasie the overlap of the diagnostic criteria.
Keywords
- Type
- Brief Report
- Information
- Copyright
- © The Author(s), 2021. Published by Cambridge University Press
References
Whittaker, E, Bamford, A, Kenny, J, et al. Clinical characteristics of 58 children with a pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2. JAMA 2020; 324: 259–269. DOI: 10.1001/jama.2020.10369.10.1001/jama.2020.10369CrossRefGoogle ScholarPubMed
Gardner-Medwin, JM, Dolezalova, P, Cummins, C, Southwood, TR. Incidence of Henoch-Schonlein purpura, Kawasaki disease, and rare vasculitides in children of different ethnic origins. Lancet 2002; 360: 1197–1202. DOI: 10.1016/S0140-6736(02)11279-7.CrossRefGoogle ScholarPubMed
Kanegaye, JT, Wilder, MS, Molkara, D, et al. Recognition of a Kawasaki disease shock syndrome. Pediatrics 2009; 123: e783–e789.CrossRefGoogle ScholarPubMed
Gamez-Gonzalez, LB, Moribe-Quintero, I, Cisneros-Castolo, M, et al. Kawasaki disease shock syndrome: unique and severe subtype of Kawasaki disease. Pediatr Int 2018; 60: 781–790.10.1111/ped.13614CrossRefGoogle ScholarPubMed
Noval Rivas, M, Porritt, RA, Cheng, MH, Bahar, I, Arditi, M. COVID-19-associated multisystem inflammatory syndrome in children (MIS-C): a novel disease that mimics toxic shock syndrome the superantigen hypothesis. J Allergy Clin Immunol 2021; 147: 57–59. DOI: 10.1016/j.jaci.2020.10.008.CrossRefGoogle ScholarPubMed
Iglesias-Amaya, A, Quezada-Ortega, G, Godinez-Victoria, M, et al. Kawasaki disease shock syndrome: a different subtype of Kawasaki disease? Poster 994 presented in EAP 2019 Congress. Eur J Ped 2019; 178: 1645.Google Scholar
Calcaterra, G, Mehta, JL, Fanos, V, Bassareo, PP. Insights on Kawasaki disease and multisystem inflammatory syndrome: relationship with COVID-19 infection. Editorial Minerva Pediatr (Torino) 2021; 73: 203–208. DOI: 10.23736/S0026-4946.20.06140-X.Google ScholarPubMed
Varga, Z, Flammer, AJ, Steiger, P, et al. Endothelial cell infection and endotheliitis in COVID-19. Lancet 2020; 395: 1417–1418. DOI: 10.1016/S0140-6736(20)30937-5.10.1016/S0140-6736(20)30937-5CrossRefGoogle ScholarPubMed
Yonker, LM, Gilboa, T, Ogata, A, et al. Multisystem inflammatory syndrome in children is driven by zonulin-dependent loss of gut mucosal barrier. J Clin Invest 2021; 131: 149633. DOI: 10.1172/JCI149633.CrossRefGoogle ScholarPubMed
Sancho-Shimizu, V, Brodin, P, Cobat, A, et al. SARS-CoV2-related MIS-C: a key to the viral and genetic causes of Kawasaki disease? J Exp Med 2021; 218: e20210446. DOI: 10.1084/jem.20210446.CrossRefGoogle Scholar
- 5
- Cited by