Hostname: page-component-586b7cd67f-tf8b9 Total loading time: 0 Render date: 2024-11-20T06:52:26.192Z Has data issue: false hasContentIssue false

Kawasaki disease shock syndrome in the COVID-19 pandemic

Published online by Cambridge University Press:  19 July 2021

Luisa B. Gámez-González*
Affiliation:
Immunology Department, Hospital Infantil de Especialidades de Chihuahua, Chihuahua, Mexico
Moises J. Ramírez-López
Affiliation:
Department of Infectious Diseases, Hospital Infantil de Especialidades de Chihuahua, Chihuahua, Mexico
Marcela Colmenero-Rascón
Affiliation:
Cardiology Department, Hospital Angeles Chihuahua, Chihuahua, Mexico
Marco A. Yamazaki-Nakashimada
Affiliation:
Immunology Department, Instituto Nacional de Pediatría, Mexico City, Mexico
*
Author for correspondence: L. B. Gámez-González, Immunology Department, Hospital Infantil de Especialidades de Chihuahua, Av. Prolongación Pacheco, 31090Chihuahua, Mexico. Tel: 614 1227569; Fax: 434-04-00. E-mail: [email protected]

Abstract

Multisystem inflammatory syndrome in children is a new entity in association with SARS-CoV2. Clinical features of Kawasaki disease were noted from the first reported cases of MIS-C. Before the COVID-19 pandemic, Kawasaki disease shock syndrome was considered to be a distinct and unique form of KD. We present a representative case that prove the current difficulty in clearly distinguishing MIS-C from pre-COVID-19-KDSS and emphasie the overlap of the diagnostic criteria.

Type
Brief Report
Copyright
© The Author(s), 2021. Published by Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Whittaker, E, Bamford, A, Kenny, J, et al. Clinical characteristics of 58 children with a pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2. JAMA 2020; 324: 259269. DOI: 10.1001/jama.2020.10369.10.1001/jama.2020.10369CrossRefGoogle ScholarPubMed
Gardner-Medwin, JM, Dolezalova, P, Cummins, C, Southwood, TR. Incidence of Henoch-Schonlein purpura, Kawasaki disease, and rare vasculitides in children of different ethnic origins. Lancet 2002; 360: 11971202. DOI: 10.1016/S0140-6736(02)11279-7.CrossRefGoogle ScholarPubMed
Kanegaye, JT, Wilder, MS, Molkara, D, et al. Recognition of a Kawasaki disease shock syndrome. Pediatrics 2009; 123: e783e789.CrossRefGoogle ScholarPubMed
Gamez-Gonzalez, LB, Moribe-Quintero, I, Cisneros-Castolo, M, et al. Kawasaki disease shock syndrome: unique and severe subtype of Kawasaki disease. Pediatr Int 2018; 60: 781790.10.1111/ped.13614CrossRefGoogle ScholarPubMed
Noval Rivas, M, Porritt, RA, Cheng, MH, Bahar, I, Arditi, M. COVID-19-associated multisystem inflammatory syndrome in children (MIS-C): a novel disease that mimics toxic shock syndrome the superantigen hypothesis. J Allergy Clin Immunol 2021; 147: 5759. DOI: 10.1016/j.jaci.2020.10.008.CrossRefGoogle ScholarPubMed
Iglesias-Amaya, A, Quezada-Ortega, G, Godinez-Victoria, M, et al. Kawasaki disease shock syndrome: a different subtype of Kawasaki disease? Poster 994 presented in EAP 2019 Congress. Eur J Ped 2019; 178: 1645.Google Scholar
Calcaterra, G, Mehta, JL, Fanos, V, Bassareo, PP. Insights on Kawasaki disease and multisystem inflammatory syndrome: relationship with COVID-19 infection. Editorial Minerva Pediatr (Torino) 2021; 73: 203208. DOI: 10.23736/S0026-4946.20.06140-X.Google ScholarPubMed
Varga, Z, Flammer, AJ, Steiger, P, et al. Endothelial cell infection and endotheliitis in COVID-19. Lancet 2020; 395: 14171418. DOI: 10.1016/S0140-6736(20)30937-5.10.1016/S0140-6736(20)30937-5CrossRefGoogle ScholarPubMed
Yonker, LM, Gilboa, T, Ogata, A, et al. Multisystem inflammatory syndrome in children is driven by zonulin-dependent loss of gut mucosal barrier. J Clin Invest 2021; 131: 149633. DOI: 10.1172/JCI149633.CrossRefGoogle ScholarPubMed
Sancho-Shimizu, V, Brodin, P, Cobat, A, et al. SARS-CoV2-related MIS-C: a key to the viral and genetic causes of Kawasaki disease? J Exp Med 2021; 218: e20210446. DOI: 10.1084/jem.20210446.CrossRefGoogle Scholar