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High prevalence of ascending aortic dilation in adults with repaired coarctation of the aorta

Part of: Echocardiography

Published online by Cambridge University Press:  18 February 2021

Daniel Rinnström Open the ORCID record for Daniel Rinnström [Opens in a new window] ,
Mikael Dellborg ,
Ulf Thilén ,
Peder Sörensson ,
Niels-Erik Nielsen ,
Christina Christersson  and
Bengt Johansson
Daniel Rinnström*
Affiliation:
Heart Centre and Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden
Mikael Dellborg
Affiliation:
Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden
Ulf Thilén
Affiliation:
Department of Cardiology, Clinical Sciences, Lund University, Lund, Sweden
Peder Sörensson
Affiliation:
Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
Niels-Erik Nielsen
Affiliation:
Department of Medical and Health Sciences, Linköping University, Linköping, Sweden
Christina Christersson
Affiliation:
Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden
Bengt Johansson
Affiliation:
Heart Centre and Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden
*
Author for correspondence: Dr D. Rinnström, Heart Centre and Department of Public Health and Clinical Medicine, Umeå University, Sweden. Tel: +46 (0)70 3416796. E-mail: [email protected]
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Abstract

Background:

Ascending aortic dilation is a feared complication in adults with repaired coarctation of the aorta, as the condition is associated with life-threatening complications such as aortic dissection and rupture. However, the data are currently limited regarding factors associated with ascending aortic dilation in these patients.

Methods and results:

From the national register of congenital heart disease, 165 adult patients (≥ 18 years old) with repaired coarctation of the aorta, and echocardiographic data on aortic dimensions, were identified (61.2% male, mean age 35.8 ± 14.5 years). Aortic dilation (aortic diameters > 2 SD above reference mean) was found in 55 (33.3%) of the 165 included patients, and was associated with manifest aortic valve disease in univariable logistic regression analysis (OR 2.44, 95% CI [1.23, 4.83]).

Conclusions:

Aortic dilation is common post-repair of coarctation of the aorta, and is associated with manifest aortic valve disease and thus indirectly with the presence of a bicuspid aortic valve. However, no association was found between aortic dilation and age or blood pressure.

Keywords

CoAGUCHaortic dilation
Type
Original Article
Information
Cardiology in the Young , Volume 31 , Issue 6 , June 2021 , pp. 992 - 997
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Copyright
© The Author(s), 2021. Published by Cambridge University Press

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