Hostname: page-component-586b7cd67f-g8jcs Total loading time: 0 Render date: 2024-11-23T09:08:14.133Z Has data issue: false hasContentIssue false
  • English
  • Français

Fibromuscular dysplasia as the substrate for systemic and pulmonary hypertension in the setting of Moya-Moya disease

Published online by Cambridge University Press:  20 September 2006

Phalla Ou ,
Peggy Dupont  and
Damien Bonnet
Phalla Ou
Affiliation:
Cardiologie Pédiatrique, Hôpital Necker-Enfants Malades, AP-HP, Paris, France
Peggy Dupont
Affiliation:
Cardiologie Pédiatrique, Hôpital Necker-Enfants Malades, AP-HP, Paris, France
Damien Bonnet
Affiliation:
Cardiologie Pédiatrique, Hôpital Necker-Enfants Malades, AP-HP, Paris, France
Get access Rights & Permissions [Opens in a new window]

Abstract

We report the first case, to the best of our knowledge, of a child with the unusual association of Moya-Moya disease and both systemic and pulmonary hypertension. Histological examination revealed fibromuscular dysplasia as the common denominator for a diffuse arteriopathy.

Keywords

Pulmonary arterial stenosisrenal arterial stenosiscerebrovascular pathology
Type
Brief Report
Information
Cardiology in the Young , Volume 16 , Issue 5 , October 2006 , pp. 495 - 497
Copyright
© 2006 Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Natori Y, Ikezaki K, Matsushima T, Fukui M. “Angiographic moyamoya” its definition, classification, and therapy. Clin Neurol Neurosurg 1997; 99 (Suppl 2): S168–S172.Google Scholar
Choi Y, Kang BC, Kim KJ, et al. Renovascular hypertension in children with moyamoya disease. J Pediatr 1997; 131: 258–263.Google Scholar
Kapusta L, Daniels O, Renier WO. Moya-Moya syndrome and primary pulmonary hypertension in childhood. Neuropediatrics 1990; 21: 162–163.Google Scholar
de Vries RR, Nikkels PG, van der Laag J, Broere G, Braun KP. Moyamoya and extracranial vascular involvement: fibromuscular dysplasia? A report of two children. Neuropediatrics 2003; 34: 318–321.Google Scholar
Fukuhara H, Kitayama H, Yokoyama T, Shirotani H. Thromboembolic pulmonary hypertension due to disseminated fibromuscular dysplasia. Pediatr Cardiol 1996; 17: 340–345.Google Scholar
Slovut DP, Olin JW. Fibromuscular dysplasia. N Engl J Med 2004; 350: 1862–1871.Google Scholar
Sang CN, Whelton PK, Hamper UM, et al. Etiologic factors in renovascular fibromuscular dysplasia. A case-control study. Hypertension 1989; 14: 472–479.Google Scholar
Pannier-Moreau I, Grimbert P, Fiquet-Kempf B, et al. Possible familial origin of multifocal renal artery fibromuscular dysplasia. J Hypertens 1997; 15: 1797–1801.Google Scholar
Bofinger A, Hawley C, Fisher P, Daunt N, Stowasser M, Gordon R. Polymorphisms of the renin-angiotensin system in patients with multifocal renal arterial fibromuscular dysplasia. J Hum Hypertens 2001; 15: 185–190.Google Scholar
Isono M, Ishii K, Kamida T, Inoue R, Fujiki M, Kobayashi H. Long-term outcomes of pediatric moyamoya disease treated by encephalo-duro-arterio-synangiosis. Pediatr Neurosurg 2002; 36: 14–21.Google Scholar