Hostname: page-component-cd9895bd7-8ctnn Total loading time: 0 Render date: 2024-12-23T09:07:41.405Z Has data issue: false hasContentIssue false
  • English
  • Français

Coronary artery spasm due to intravenous atropine infusion in a child: possible Kounis syndrome

Published online by Cambridge University Press:  10 January 2018

Ana Castellano-Martinez  and
Moises Rodriguez-Gonzalez
Ana Castellano-Martinez
Affiliation:
Department of Pediatrics, Hospital Universitario Puerta del Mar, Cadiz, Spain
Moises Rodriguez-Gonzalez*
Affiliation:
Department of Pediatric Cardiology, Hospital Universitario Puerta del Mar, Cadiz, Spain
*
Correspondence to: M. Rodriguez-Gonzalez, MD, Department of Pediatrics, Hospital Universitario Puerta del Mar, Ana de Viya Avenue 34, 11009 Cadiz, Spain. Tel: 34 956 00 27 00; Fax: 34 956002085; E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Coronary vasospasm can result from silent myocardial ischaemia to sudden death. There are many precipitant factors including different pharmacological agents. Kounis syndrome is defined by acute coronary syndromes associated with anaphylactic or anaphylactoid reactions. We report, to the best of our knowledge, the first paediatric case of Kounis syndrome due to intravenous atropine.

Keywords

Atropinecoronary vasospasmKounis syndromechildren
Type
Brief Report
Information
Cardiology in the Young , Volume 28 , Issue 4 , April 2018 , pp. 616 - 618
Check for updates
Copyright
© Cambridge University Press 2018 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Ming-Jui, H, Hu, P, Ming-Yow, H. Coronary artery spasm: review and update. Int J Med Sci 2014; 11: 1161–1171.Google Scholar
2. Miwa, K, Nakagawa, K, Yoshida, N, et al. Lipoprotein (a) is a risk factor for occurrence of acute myocardial infarction in patients with coronary vasospasm. J Am Coll Cardiol 2000; 35: 1200–1205.Google Scholar
3. Jasmin, R, Ng, C-T, Sockalingam, S, et al. Myocardial infarction with normal coronaries: an unexpected finding in a 13-year-old girl with systemic lupus erythematosus. Lupus 2013; 22: 1518–1522.CrossRefGoogle Scholar
4. Subramanian, S, Gaum, WE. Acute myocardial infarction caused by transient coronary vasospasm in a child with Kawasaki disease and no coronary aneurysms. Pediatr Cardiol 2010; 31: 875–877.Google Scholar
5. Lee, J, Seok, J, Kim, Y, et al. Atropine injection followed by coronary artery spasm with ventricular tachycardia during spinal anesthesia. Korean J Anesthesiol 2013; 65: 66–70.CrossRefGoogle ScholarPubMed
6. Kounis, NG. Kounis syndrome: an update on epidemiology, pathogenesis, diagnosis and therapeutic management. Clin Chem Lab Med 2016; 54: 1545–1559.Google Scholar
7. Biteker, M, Duran, NE, Biteker, F, et al. Kounis syndrome: first series in Turkish patients. Anadolu Kardiyol Derg 2009; 9: 59–60.Google ScholarPubMed
8. Ebo, DG, Leysen, J, Mayorga, C, et al. The in vitro diagnosis of drug allergy: status and perspectives. Allergy 2011; 66: 1275–1286.Google Scholar
9. Demoly, P, Adkinson, NF, Brockow, K, et al. International consensus on drug allergy. Allergy 2014; 69: 420–437.Google Scholar
10. Brockow, K, Garvey, LH, Aberer, W, et al. Skin test concentrations for systemically administered drugs – an ENDA/EAACI Drug Allergy Interest Group position paper. Allergy 2013; 68: 702–712.CrossRefGoogle ScholarPubMed