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Cardiovascular and metabolic risk markers are related to parasympathetic indices in pre-pubertal adolescents

Published online by Cambridge University Press:  24 February 2015

Suziane U. Cayres ,
Luiz Carlos M. Vanderlei ,
Danilo R. P. Silva ,
Manoel Carlos S. Lima ,
Maurício F. Barbosa  and
Rômulo A. Fernandes
Suziane U. Cayres*
Affiliation:
Post-Graduate Program in Movement Sciences, Sao Paulo State University, Rio Claro, Brazil Laboratory of Investigation in Exercise, Department of Physical Education, São Paulo State University, Presidente Prudente, Brazil
Luiz Carlos M. Vanderlei
Affiliation:
Department of Physical Therapy, Sao Paulo State University, Presidente Prudente, Sao Paulo, Brazil
Danilo R. P. Silva
Affiliation:
Center of Physical Education and Sport, Londrina State University, Londrina, Brazil
Manoel Carlos S. Lima
Affiliation:
Post-Graduate Program in Movement Sciences, Sao Paulo State University, Rio Claro, Brazil Laboratory of Investigation in Exercise, Department of Physical Education, São Paulo State University, Presidente Prudente, Brazil
Maurício F. Barbosa
Affiliation:
Program of Post-Graduate in Radiology, Federal University of Sao Paulo – UNIFESP, Sao Paulo, Brazil
Rômulo A. Fernandes
Affiliation:
Post-Graduate Program in Movement Sciences, Sao Paulo State University, Rio Claro, Brazil Laboratory of Investigation in Exercise, Department of Physical Education, São Paulo State University, Presidente Prudente, Brazil
*
Correspondence to: S. U. Cayres, MSc, Department of Physical Education, Roberto Simonsen Street 305, 19060900 Presidente Prudente, São Paulo, Brazil. Tel: +183 229 5400; Fax: (18) 3221 4391; E-mail: [email protected]
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Abstract

Objective

To analyse the relationship between different heart rate variability indices, resting heart rate, and cardiovascular markers in adolescents.

Methods

A cross-sectional study was carried out with information from an ongoing cohort study. The sample was composed of 99 adolescents who complied with the following inclusion criteria: aged between 11 and 14 years; enrolled in a school unit of elementary education; absence of any known diseases; no drug consumption; and a formal consent signed by the parents or legal guardians. Weight, height, heart rate variability, lipid profile, inflammatory markers, blood pressure, resting heart rate, intima-media thickness, blood flow, and trunk fatness were measured. Partial correlation and linear regression (expressed by β and 95% confidence intervals [95%CI]) analyses were used to analyse the relationships between the variables.

Results

In the linear regression analysis, even after adjustments for sex, age, trunk fatness, and somatic maturation, parasympathetic activity presented significant correlations with maximum carotid artery blood flow (β=−0.111 [95%CI=−0.216; −0.007]), systolic blood pressure (β=−0.319 [95%CI=−0.638; −0.001]), and resting heat rate (β=−0.005 [95%CI=−0.009; −0.002]).

Conclusion

Parasympathetic activity at rest is inversely related to maximum and minimum blood flow, triacylglycerol levels, and systolic blood pressure. These findings suggest that heart rate variability has the potential to discriminate pre-pubertal adolescents at increased risk.

Keywords

Childrenatherosclerosisheart rate variabilitycardiovascular risk
Type
Original Articles
Information
Cardiology in the Young , Volume 26 , Issue 2 , February 2016 , pp. 280 - 287
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Copyright
© Cambridge University Press 2015 

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