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18F-fluorodeoxyglucose positron emission tomography/CT in the diagnosis of right-sided endocarditis in children and adults with infective endocarditis

Published online by Cambridge University Press:  02 January 2024

Sezen Ugan Atik Open the ORCID record for Sezen Ugan Atik [Opens in a new window] ,
Perver Arslan Open the ORCID record for Perver Arslan [Opens in a new window] ,
Seçkin Bilgiç Open the ORCID record for Seçkin Bilgiç [Opens in a new window] ,
Kerim Sonmezoglu Open the ORCID record for Kerim Sonmezoglu [Opens in a new window] ,
Erman Cilsal Open the ORCID record for Erman Cilsal [Opens in a new window] ,
Selman Gokalp Open the ORCID record for Selman Gokalp [Opens in a new window]  and
Alper Guzeltas Open the ORCID record for Alper Guzeltas [Opens in a new window]
Sezen Ugan Atik*
Affiliation:
Department of Pediatric Cardiology, University of Health Sciences, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey
Perver Arslan
Affiliation:
Department of Pediatric Cardiology, University of Health Sciences, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey
Seçkin Bilgiç
Affiliation:
Department of Nuclear Medicine, Istanbul University Cerrahpaþa Faculty of Medicine, Istanbul, Turkey
Kerim Sonmezoglu
Affiliation:
Department of Nuclear Medicine, Istanbul University Cerrahpaþa Faculty of Medicine, Istanbul, Turkey
Erman Cilsal
Affiliation:
Department of Pediatric Cardiology, University of Health Sciences, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey
Selman Gokalp
Affiliation:
Department of Pediatric Cardiology, University of Health Sciences, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey
Alper Guzeltas
Affiliation:
Department of Pediatric Cardiology, University of Health Sciences, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey
*
Corresponding author: S. Ugan Atik; Email: [email protected]
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Abstract

Objective:

Infectious endocarditis poses a diagnostic challenge due to its highly variable clinical presentation. To establish a definitive diagnosis, different imaging modalities are essential. In recent years, positron emission tomography/CT has gained increasing significance in diagnosing infective endocarditis; however, its application in the pediatric age group remains limited. This study encompasses patients definitively or potentially diagnosed with infectious endocarditis at our institution from 2018 to 2023.

Methods:

A total of 29 patients underwent 18F-fluorodeoxyglucose positron emission tomography/CT examinations, with 19 of them presenting with right-sided infective endocarditis.

Results:

Evidence consistent with infective endocarditis was observed in 18 (94.7%) of the patients. Pulmonary septic embolism was identified in 15 (78.9%) cases, and splenic involvement was noted in 12 (57.8%) cases. Transthoracic/transesophageal echocardiography failed to reveal vegetation or provided uncertain results in six patients, whereas fluorodeoxyglucose-positron emission tomography-CT exhibited involvement. Subsequently, the diagnosis of infective endocarditis was confirmed post-surgery based on the fluorodeoxyglucose-positron emission tomography-CT findings.

Conclusion:

Our results, along with our clinical experience, demonstrate that fluorodeoxyglucose-positron emission tomography-CT is a safe and viable method for diagnosing right-sided endocarditis, which is often challenging to visualize using echocardiography.

Keywords

paediatric cardiologyınfective endocarditis18F-fluorodeoxyglucose positron emission tomography/CT
Type
Original Article
Information
Cardiology in the Young , Volume 34 , Issue 6 , June 2024 , pp. 1226 - 1231
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Copyright
© The Author(s), 2024. Published by Cambridge University Press

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