Hostname: page-component-78c5997874-94fs2 Total loading time: 0 Render date: 2024-11-17T16:50:11.320Z Has data issue: false hasContentIssue false
  • English
  • Français

Cause, Care, Cure: Research Priorities for Alzheimer’s Disease and Related Dementias*

Published online by Cambridge University Press:  01 November 2011

Paul Stolee ,
Loretta M. Hillier ,
Sheila Cook  and
Kenneth Rockwood
Paul Stolee*
Affiliation:
School of Public Health and Health Systems, University of Waterloo
Loretta M. Hillier
Affiliation:
Rehabilitation and Geriatric Care Research Centre of the Lawson Health Research Institute, St. Joseph’s Health Care London
Sheila Cook
Affiliation:
Infacilitation, London, Ontario
Kenneth Rockwood
Affiliation:
Department of Medicine, Dalhousie University
*
†Correspondence and requests for offprints should be sent to / La correspondance et les demandes de tirés-à-part doivent être adressées à: Paul Stolee, Ph.D. School of Public Health and Health Systems 200 University Avenue West University of Waterloo Waterloo, ON N2L 3G1 ([email protected])
Get access Rights & Permissions [Opens in a new window]

Abstract

Part of Ontario’s strategy on Alzheimer’s disease and related dementias (ADRD) was to develop research priorities and recommend strategies for building research capacity. The process to achieve these objectives included an environmental scan, key informant interviews, surveys, and a consensus workshop; this process involved over 100 researchers, clinicians, persons with early dementia, and family caregivers. This article describes the process undertaken, key issues identified, and recommendations for research priorities and for building research capacity; and provides a strategic direction for dementia research in Ontario that is relevant for other jurisdictions. ADRD research in all aspects is required to advance knowledge of ADRD cause, care, and cure; gaps currently exist in understanding effective approaches to care and knowledge transfer. Capacity for high-calibre research hinges on maintaining attractive career paths for researchers, solid infrastructures, and strong partnerships. For research to inform policy and practice, better mechanisms are needed for knowledge exchange.

Résumé

Une partie de la stratégie de l’Ontario sur la maladie d’Alzheimer et les démences connexes (MADC) était de développer les priorités de recherche et de recommander des stratégies pour le renforcement des capacités de recherche. Le processus adopté pour atteindre ces objectifs comprenaient une analyse de l’environnement, des entretiens avec les informateurs clés, des enquêtes et un atelier de consensus ; ce processus a impliqué plus de 100 chercheurs, cliniciens, les personnes atteintes de démence précoce, et les aidants membres de familles. Ce document décrit le processus entrepris, les principaux problèmes identifiés et les recommandations pour les priorités de recherche et de renforcement des capacités de recherche ; il fournit également une orientation stratégique pour la recherche sur la démence en Ontario qui est pertinente pour d’autres juridictions. La recherche MADC dans tous ses aspects est nécessaire pour faire progresser la connaissance des causes de la démence, les soins et la guérison ; des lacunes existent actuellement dans la compréhension des approches efficaces pour les soins et le transfert des connaissances. La capacité pour la recherche de haut calibre reste sur le maintien de plans de carrière attractifs pour les chercheurs, des infrastructures solides et de partenariats forts. Afin que la recherche informera les politiques et pratiques, de meilleurs mécanismes seront nécessaires pour l’échange de connaissances.

Keywords

la maladie d’Alzheimerla démencepriorité de recherchecapacité de rechercheAlzheimer’s diseasedementiaresearch prioritiesresearch capacity
Type
Policy and Practice Note / Note de politique et practique
Information
Canadian Journal on Aging / La Revue canadienne du vieillissement , Volume 30 , Issue 4 , December 2011 , pp. 657 - 667
Copyright
Copyright © Canadian Association on Gerontology 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

*

This research-priority-setting initiative was funded by the Government of Ontario and managed by the Alzheimer Society of Ontario. We acknowledge Jenna Hollomby for her assistance with the planning and implementation of the consensus workshop. We are grateful for the contributions of all those individuals who participated in this priority setting process, and for guidance received from the members of the project Advisory Committee: Michael Borrie, University of Western Ontario; Larry W. Chambers, Élisabeth Bruyère Research Institute; Lorna de Wit, McMaster University; Sherry Dupuis, University of Waterloo; Nathan Herrmann, University of Toronto; Robert Hopkins, Kingston Psychiatric Hospital; Howard Mount, University of Toronto; Raymond Pong, Laurentian University; Parminder Raina, McMaster University; Nalini Rattan, Alzheimer Society of Canada; Ekaterina Rogaeva, University of Toronto; Jane Rylett, University of Western Ontario; Linda Stebbins, Alzheimer Society of Ontario; and Irene Turpie, McMaster University; and ex-officio members: Elizabeth Esteves, Ontario Seniors’ Secretariat; Angie Szuch, Ontario Seniors’ Secretariat; Eric Hong, Alzheimer Society of Ontario; Michael Klejman, Ontario Ministry of Health and Long-Term Care; and Caroline Lonsdale, Ontario Ministry of Health and Long-Term Care.

References

æstima research. (2004). Research priorities for Alzheimer disease and related dementias. Environmental scan. Waterloo, Ontario, Canada: Author.Google Scholar
æstima research. (2005a). Research priorities for Alzheimer disease and related dementias. Consensus Workshop Report. Waterloo, Ontario, Canada: Author.Google Scholar
æstima research. (2005b). Research priorities for Alzheimer disease and related dementias. Report on qualitative interviews. Waterloo, Ontario, Canada: Author.Google Scholar
æstima research. (2005c). Research priorities for Alzheimer disease and related dementia. Quantitative Survey Report. Waterloo, Ontario, Canada: Author.Google Scholar
Alzheimer Society of Canada. (2010). Rising tide: The impact of dementia on Canadian society. Toronto, Ontario, Canada: Author.Google Scholar
Boise, L., Camicioli, R., Morgan, D.L., Rose, J.H., & Congleton, L. (1999). Diagnosing dementia: Perspectives of primary care physicians. The Gerontologist, 39, 447–455.CrossRefGoogle ScholarPubMed
Burton, L.C., Zdaniuk, B., Schultz, R., Jackson, S., & Hirsch, C. (2003). Transitions in spousal caregiving. The Gerontologist, 43, 230–241.CrossRefGoogle ScholarPubMed
Callahan, C.M., Boustani, M.A., Unverzagt, F.W., Austrom, M.G., Damush, T.M., Perkins, A.J. et al. . (2006). Effectiveness of collaborative care for older adults with Alzheimer disease in primary care: A randomized trial Journal of the American Medical Association, 295, 2148–2157.CrossRefGoogle Scholar
Chambers, L.W., Hendriks, A., Hall, H.L., Raina, P., McDowell, I., & the “Care for the Caregiver” Working Group. (2004). Research on Alzheimer’s caregiving in Canada: Current status and future directions. Chronic Diseases in Canada, 25., 108–118.Google ScholarPubMed
Chambers, L.W., Luesby, D., Brookman, C., Harris, M., & Lusk, E. (2010). The Seniors Health Research Transfer Network knowledge exchange model: System-wide implementation for health and healthcare for seniors. Healthcare Management Forum, 23, 4–9.CrossRefGoogle Scholar
Chertkow, H. (2007). Introduction: The Third Canadian Consensus Conference on the Diagnosis and Treatment of Dementia, 2006. Alzheimer’s and Dementia, 3, 262–265.CrossRefGoogle ScholarPubMed
Hoenig, H., & Siebens, H. (2004). Research agenda for geriatric rehabilitation. American Journal of Physical Medicine and Rehabilitation, 83, 858–866.CrossRefGoogle ScholarPubMed
Iliffe, S., & Manthorpe, J. (2002). Dementia in the community: Challenges for primary care development. Reviews in Clinical Gerontology, 12, 243–252.CrossRefGoogle Scholar
Lawton, M.P. (1996). Behavorial problems and interventions in Alzheimer’s disease: Research needs. International Psychogeriatrics, 8, 95–98.CrossRefGoogle Scholar
Neurological Health Charities Canada. (2010). A brain strategy for Canada. Toronto, Ontario, Canada: Author.Google Scholar
Ontario Ministry of Health and Long-Term Care. (1994). Ontario’s strategy for Alzheimer disease and related dementias—Preparing for our future. Toronto, Ontario, Canada: Queen’s Printer for Ontario.Google Scholar
Ontario Neurological Joint Working Group. (2010). Wired for success: Toward an Ontario brain strategy. Toronto, Ontario, Canada: Neurological Health Charities Canada.Google Scholar
Patterson, C.J., Gauthier, S., Bergman, H., Cohen, C.A., Feightner, J.W., Feldman, H. et al. . (1999). The recognition, assessment, and management of dementing disorders: Conclusions from the Canadian Consensus Conference on Dementia. Canadian Medical Association Journal, 160, S1–S15.Google ScholarPubMed
Peacock, S.C., & Forbes, D.A. (2003). Interventions for caregivers of persons with dementia: A systematic review. Canadian Journal of Nursing Research, 35, 88–107.Google ScholarPubMed
Rockwood, K., & Keren, R. (2010). Dementia services in Canada. International Journal of Geriatric Psychiatry, 25, 876–880.CrossRefGoogle ScholarPubMed
Sachs, G.A., Shega, J.W., & Cox-Hayley, D. (2004). Barriers to excellent end-of-life care for patients with dementia. Journal of General Intern Medicine, 19, 1057–1063.CrossRefGoogle ScholarPubMed
Schölzel-Dorenbos, C.J.M., Meeuwsen, E.J., & Olde Rikkert, M.G.M. (2010). Integrating unmet needs into dementia health-related quality of life research and care: Introduction of the Hierarchy Model of Needs in Dementia. Aging and Mental Health, 14, 113–119.CrossRefGoogle ScholarPubMed
Schulz, R., & Martire, L.M. (2004). Family caregiving of persons with dementia. Prevalence, health effects, and support strategies. American Journal of Geriatric Psychiatry, 12, 240–249.CrossRefGoogle ScholarPubMed
Sidorenko, A., & Walker, A. (2004). The Madrid International Plan of Action on Ageing: From conception to implementation. Ageing and Society, 24, 147–165.CrossRefGoogle Scholar
Solomon, D.H., LoCicero, J., & Rosenthal, R.A. (2004). New frontiers in geriatric research. An agenda for surgical and medical specialities. New York: American Geriatrics Society.Google Scholar
Stolee, P., Borrie, M.J., Cook, S., Hollomby, J., & the participants of the Canadian Consensus Workshop on Geriatric Rehabilitation. (2004). A research agenda for geriatric rehabilitation: The Canadian Consensus. Geriatrics Today: Journal of the Canadian Geriatrics Society, 7, 38–42.Google Scholar
Stolee, P., McAiney, C., Hillier, L.M., Hamilton, P., Kessler, L., Madsen, V. et al. . (2009). Sustained transfer of knowledge to practice in long-term care: Facilitators and barriers of a mental health learning initiative. Gerontology and Geriatrics Education, 30, 1–20.CrossRefGoogle ScholarPubMed
Teel, C.S. (2004). Rural practitioners’ experiences in dementia diagnosis and treatment. Aging and Mental Health, 8, 422–429.CrossRefGoogle ScholarPubMed
Valcour, V.G., Masaki, K.H., Curb, D., & Blanchette, P.L. (2000). The detection of dementia in the primary care setting. Archives of Internal Medicine, 160, 2964–2968.CrossRefGoogle ScholarPubMed
Vellas, B., Reynish, E., & Robert, P. (2007). Commentary on “The Third Canadian Consensus Conference on the Diagnosis and Treatment of Dementia, 2006”. Alzheimer’s and Dementia, 3, 444–445.CrossRefGoogle Scholar