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Use of a Synaptosomal Model to Monitor Drug-Induced in vivo Changes in the γ-Aminobutyric Acid Content of Nerve Endings and its Relevance to Research on Antipsychotic Drugs

Published online by Cambridge University Press:  18 September 2015

J.D. Wood
J.D. Wood*
Affiliation:
Department of Biochemistry, University of Saskatchewan, Saskatoon
*
Department of Biochemistry, University of Saskatchewan, Saskatoon, Canada S7N 0W0
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The validity of a synaptosomal model to monitor drug-induced changes in the y-aminobutyric acid (GABA) content of nerve endings is reviewed. Examples of data obtained using the model are presented and the possibility of using the model for research on antipsychotic drugs is discussed.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 7 , Issue 3 , August 1980 , pp. 253 - 255
Copyright
Copyright © Canadian Neurological Sciences Federation 1980

References

REFERENCES

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