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Tremorgenic Encephalopathy: A Role of Mycotoxins in the Production of CNS Disease in Humans?

Published online by Cambridge University Press:  18 September 2015

K.E. Gordon ,
R.E. Masotti  and
W.R. Waddell
K.E. Gordon*
Affiliation:
Department of Pediatrics, Dalhousie University, Halifax (K.E.G.); Department of Pediatrics, Queen's University, Kingston (R.E.M.); Occupational Health Medical Service, Ontario Ministry of Labour, Kingston (W.R.W.)
R.E. Masotti*
Affiliation:
Department of Pediatrics, Dalhousie University, Halifax (K.E.G.); Department of Pediatrics, Queen's University, Kingston (R.E.M.); Occupational Health Medical Service, Ontario Ministry of Labour, Kingston (W.R.W.)
W.R. Waddell*
Affiliation:
Department of Pediatrics, Dalhousie University, Halifax (K.E.G.); Department of Pediatrics, Queen's University, Kingston (R.E.M.); Occupational Health Medical Service, Ontario Ministry of Labour, Kingston (W.R.W.)
*
IWK Children's Hospital, 5850 University Avenue, Box 3070, Halifax, Nova Scotia, Canada B3J 3G9
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Abstract:

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We describe a young man who, shortly after exposure to moldy silage, developed a neurological syndrome consisting of dementia and a remarkable tremor which was precipitated by movement. All symptoms resolved within one week. Despite investigation, no definitive diagnosis was reached. We propose that this patient's illness may have resulted from inhalation exposure to a tremorgenic mycotoxin.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 20 , Issue 3 , August 1993 , pp. 237 - 239
Copyright
Copyright © Canadian Neurological Sciences Federation 1993

References

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