Hostname: page-component-78c5997874-j824f Total loading time: 0 Render date: 2024-11-16T15:13:04.354Z Has data issue: false hasContentIssue false

Surgical Referral for Carotid Artery Stenosis — The Influence of NASCET

Published online by Cambridge University Press:  18 September 2015

T.J. Coyne*
Affiliation:
Division of Neurosurgery, The Toronto Hospital and University of Toronto, Toronto
M.C. Wallace
Affiliation:
Division of Neurosurgery, The Toronto Hospital and University of Toronto, Toronto
*
Division of Neurosurgery, The Toronto Hospital, 399 Bathurst Sreet, Toronto, Ontario, Canada M5T 2S8
Rights & Permissions [Opens in a new window]

Abstract:

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

A retrospective review was undertaken of 139 consecutive patients with presumed carotid artery stenosis referred to a vascular neurosurgeon. The review period included three years prior and one year subsequent to the publication of the North American Symptomatic Carotid Endarterectomy Trial (NASCET) preliminary results showing surgery to be superior to best medical therapy for patients with symptomatic, high grade (> 70% linear diameter) carotid stenosis. The aims of this analysis were to determine any changes in the referral pattern following the NASCET publication (post-NASCET), and to examine the use and reliability for surgical decision making of pre-referral carotid artery imaging. Patient referral rate increased markedly post-NASCET, particularly from neurologists. There was a trend for more post-NASCET referrals to be for high grade stenosis and fewer referrals to be for intermediate grade (30-69% linear diameter) stenosis, although continued referral of patients with intermediate grade stenosis is desirable as randomization into NASCET continues for this group of patients. Ninety-six patients (69%) were referred with carotid duplex ultrasonography having been performed. There was poor correlation of these results with angiography, which remains necessary for planning management. A majority of patients (65%) referred to this surgical practice did not come to surgery.

Résumé:

RÉSUMÉ:

Nous avons revisé les cas de 139 patients consécutifs référés à un chirurgien vasculaire pour sténose carotidienne. Ces cas avaient été référés sur une période de trois ans avant et d'un an après la publication des résultats préliminaires de l'étude nord-américaine sur l'endartérectomie carotidienne chez les patients symptômatiques (North American Symptomatic Carotid Endarterectomy Trial — NASCET) montrant que la chirurgie était supérieure au meilleur traitement médical chez les patients symptômatiques, porteurs d'une sténose carotidienne sévère (> 70% de diamètre linéaire). Les buts de cette analyse étaient de déterminer s'il y avait eu des changements dans les habitudes de référence suite à la publication de NASCET (post-NASCET) et d'examiner l'utilité et la fiabilité de l'imagerie carotidienne faite avant la consultation en chirurgie vasculaire pour la prise de décision chirurgicale. Le taux de référence a augmenté considérablement post-NASCET, surtout de la part des neurologues. Post-NASCET, les médecins avaient tendance à référer plus de patients avec une sténose sévère et moins de patients avec une sténose modérée (30-69% de diamètre linéaire). Cependant, il est souhaitable que les patients avec une sténose modérée continuent à être référés parce que la randomisation dans l'étude NASCET se poursuit pour ce groupe de patients. L'ultrasonographie duplex carotidienne avait déjà été faite avant la consultation chez quatre-vingt-seize patients (69%). La corrélation avec les résultats de l'angiographie, qui demeure nécessaire à l'établissement d'un plan de traitement, était faible. La majorité des patients (65%) qui nous ont été référés n'ont pas été soumis à la chirurgie.

Type
Articles
Copyright
Copyright © Canadian Neurological Sciences Federation 1994

References

REFERENCES

1. NASCET Investigators. Benefit of carotid endarterectomy for patients with high-grade stenosis of the internal carotid artery. Clinical Alert of the National Institute of Neurological Disorders and Stroke, Bethesda, MD, April 22, 1991.Google Scholar
2. NASCET Collaborators. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med 1991;325:445453.Google Scholar
3. European Carotid Surgery Trialists' Collaborative Group. MRC European carotid surgery trial: interim results for symptomatic patients with severe (70-99%) or with mild (0-29%) carotid stenosis. Lancet 1991; 337; 12351243.CrossRefGoogle Scholar
4. Kistler, JP, Buonanno, FS, Gress, DR. Carotid endarterectomy - specific therapy based on pathophysiology. N Engl J Med 1991; 325: 505507.CrossRefGoogle ScholarPubMed
5. Levy, LL. Carotid endarterectomy. When and why. JAMA 1991; 266: 33323333.Google ScholarPubMed
6. Barnett HJM. Carotid endarterectomy evaluation: goals common to all neurologists. Ann Neurol 1992; 32: 832833.CrossRefGoogle Scholar
7. Cusimano, MD. An update on the Carotid Endarterectomy Study. Can J Surg 1991; 34: 415.Google ScholarPubMed
8. Reinmuth, OM, Dyken, ML. Carotid endarterectomy: bright light at the end of the tunnel. Stroke 1992; 22: 835836.CrossRefGoogle Scholar
9. Smith, RR. Comment on Sieber, FE, Toung, TJ, Diringer, MN, Wang, W, Long, DM. Preoperative risks predict neurological outcome of carotid endarterectomy related stroke. Neurosurgery 1992; 30: 854.Google Scholar
10. Moore, WS, Mohr, JP, Najafi, H, et al. Carotid endarterectomy: practice guidelines. J Vase Surg 1992; 15: 469479.CrossRefGoogle ScholarPubMed
11. Barnett, HJM, Plum, F, Walton, JN. Carotid endarterectomy: an expression of concern. Stroke 1984; 15: 941943.CrossRefGoogle Scholar
12. Whisnant, JP, Fisher, L, Robertson, JT, Scheinberg, P. Does carotid endarterectomy decrease stroke and death in patients with transient ischemic attacks? Ann Neurol 1987; 22: 7276.Google Scholar
13. Barnett, HJM, Barnes, RW, Clagett, GP, et al. Symptomatic carotid artery stenosis: a solvable problem. Stroke 1992; 23: 10481053.CrossRefGoogle ScholarPubMed
14. McGahan, JP. Diagnostic ultrasound in neurological surgery. In: Youmans, JR, ed. Neurological Surgery. Philadelphia: WB Saunders; 1990: 187204.Google Scholar
15. Lewis, BD, James, M, Welch, TJ. Current applications of duplex and color flow doppler ultrasound imaging: carotid and peripheral vascular system. Mayo Clin Proc 1989; 64; 11471157.CrossRefGoogle Scholar
16. Dawson, DL, Zierler, RE, Kohler, TR. Role of arteriography in the pre-operative evaluation of carotid artery disease. Am J Surg 1991; 161: 619624.CrossRefGoogle Scholar