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Pseudoatrophy of the Brain with Valproic Acid Monotherapy

Published online by Cambridge University Press:  18 September 2015

Richard S. McLachlan
Richard S. McLachlan*
Affiliation:
Department of Clinical Neurological Sciences, The University of Western Ontario, London
*
University Hospital, 339 Windermere Road, P.O. Box 5339, Station A, London, Ontario, Canada N6A 5A5
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Abstract:

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A patient is described who, while on valproic acid monotherapy, developed reversible shrinkage of the brain, documented by computerized tomography with associated cognitive deficit. Although pseudoatrophy has been reported with steroid therapy, this is the first implication of an anticonvulsant drug in the etiology of that condition.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 14 , Issue 3 , August 1987 , pp. 294 - 296
Copyright
Copyright © Canadian Neurological Sciences Federation 1987

References

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