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Pituitary Melanocorticotrophinoma with Amyloid Deposition

Published online by Cambridge University Press:  18 September 2015

Juan M. Bilbao ,
Kalman Kovacs ,
Eva Horvath ,
Hubert P. Higgins  and
William J. Horsey
Juan M. Bilbao*
Affiliation:
Departments of Pathology, Endocrinology and Neurosurgery, St. Michael’s Hospital and University of Toronto
Kalman Kovacs
Affiliation:
Departments of Pathology, Endocrinology and Neurosurgery, St. Michael’s Hospital and University of Toronto
Eva Horvath
Affiliation:
Departments of Pathology, Endocrinology and Neurosurgery, St. Michael’s Hospital and University of Toronto
Hubert P. Higgins
Affiliation:
Departments of Pathology, Endocrinology and Neurosurgery, St. Michael’s Hospital and University of Toronto
William J. Horsey
Affiliation:
Departments of Pathology, Endocrinology and Neurosurgery, St. Michael’s Hospital and University of Toronto
*
Department of Pathology, St. Michael’s Hospital, Toronto, Ontario M5B 1W8
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Summary:

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The light and electron microscopic features of a pituitary adenoma composed of adrenocorticotrophic hormone (ACTH) and melanocyte stimulating hormone (MSH) cells with perivascular amyloid deposition is reported. Histochemical and fine structural data indicate that this material is APUDamyloid and is present in the extra-cellular perivascular spaces. It is suggested that the differences in fine structure and of distribution of the amyloid in pituitary adenomas is dependent upon the cell of origin.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 2 , Issue 3 , August 1975 , pp. 199 - 202
Copyright
Copyright © Canadian Neurological Sciences Federation 1975

References

REFERENCES

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