Background: Around 10% of ischemic stroke patients have pre-existing dementia and are excluded from stroke trials and routine care. Little is known about physician practices in the stroke care of people living with dementia (PLWD) leading to limited understanding of their experiences, priorities, and outcomes. This study aims to better understand PLWD through in-depth interviews. Methods: This study employs a qualitative descriptive methodology with two sets of 20 semi-structured interviews with PLWD and their primary caregivers (dyads), and with stroke physicians. Interviews with dyads investigate their experiences, priorities, and attitudes towards stroke care. Participants will be recruited through snowball sampling and interviews will be analyzed through qualitative data analysis software. Results: Initial analyses of the PLWD-caregiver dyad interviews have been completed, revealing themes of independence, uncertainty about the future, and fears of another stroke. Conclusions: As the population ages, stroke teams will likely encounter more PLWD. Engaging PLWD and their caregivers is crucial to better understand their experiences and priorities, which will inform future studies and improve their care. The findings from the dyad and physician interviews will be relevant to a broad audience, including patients, caregivers, physicians, researchers, and policymakers.