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P.012 Treatment and long-term follow-up of primary CNS classical Hodgkin’s Lymphoma – a case report and review of the literature

Published online by Cambridge University Press:  02 June 2017

PA Szelemej
Affiliation:
(Winnipeg)
M Bigder
Affiliation:
(Winnipeg)
J Krcek
Affiliation:
(Winnipeg)
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Abstract

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Background: Unlike non-Hodgkin’s lymphoma, central nervous system involvement with classical Hodgkin’s lymphoma is exceedingly rare, thus information regarding treatment and prognostication of the disease is lacking. Methods: This case report was prepared using hospital charts, and PubMed for the literature search. Our case was compared and contrasted against similar cases in the literature. Results: We present the case of a 47 year old female who presented with a left parietal dural-based lesion which proved to be Stage IE primary CNS classical Hodgkin’s lymphoma. After surgery and whole brain radiation therapy, the patient has remained in complete remission over nine years. Conclusions: Despite the dearth of information available regarding CNS Hodgkin’s lymphoma, our case is consistent with the findings in the literature that long-term survival is possible in patients achieving a complete response to treatment, especially in those patients who present with sole CNS involvement. To our knowledge, this represents the longest reported survival in the literature and contributes to our understanding of prognosis in patients with CNS Hodgkin’s lymphoma.

Type
Poster Presentations
Copyright
Copyright © The Canadian Journal of Neurological Sciences Inc. 2017