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Microangiography and Vascular Permeability of the Subependymal Matrix in the Premature Infant

Published online by Cambridge University Press:  18 September 2015

Sachio Takashima  and
Kenzo Tanaka
Sachio Takashima*
Affiliation:
Departments of Pediatrics and Pathology, Kyushu University, Japan, 3-1-1 Maedashi, Fukuoka, Japan
Kenzo Tanaka
Affiliation:
Departments of Pediatrics and Pathology, Kyushu University, Japan, 3-1-1 Maedashi, Fukuoka, Japan
*
Department of Pediatrics, Kyushu University, 3-1-1 Maedashi, Fukuoka 812, Japan
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Summary:

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The microvascular architecture of the subependymal matrix in premature infants was studied with microangiography and benzidine stains. This revealed that the subependymal matrix is the end zone or the border zone between cerebral arteries and the collection zone of the deep cerebral veins. Focal hypoxic changes of this subependymal matrix may occur in hypoxemia and ischemia because of the characteristic architecture.

The vascular permeability of these vessels was studied in rabbits using three different molecular weights of FITC-dextran. Vascular permeability was increased in the subependymal matrix by hypoxia and especially by hypoxia associated with an increased venous pressure. These findings may be related to the pathogenesis of subependymal hemorrhage in prematurity.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 5 , Issue 1 , February 1978 , pp. 45 - 50
Copyright
Copyright © Canadian Neurological Sciences Federation 1978

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