Hostname: page-component-586b7cd67f-rdxmf Total loading time: 0 Render date: 2024-11-22T05:58:29.351Z Has data issue: false hasContentIssue false

Management of Status Epilepticus

Published online by Cambridge University Press:  18 September 2015

Michael J. Aminoff*
Affiliation:
School of Medicine, University of California, San Francisco, California
*
Box 0114, Room M-794, University of California, San Francisco, California, U.S.A. 94143
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The pharmacologic management of major motor status epilepticus is summarized. When general anesthesia is required, the electroencephalogram (EEG) is used for monitoring the adequacy of treatment. The EEG findings may also be important in recognizing status epilepticus and monitoring its response to treatment when this is clinically difficult, as when it occurs in comatose or pharmacologically paralyzed patients or in the context of severe brain damage. Finally, the EEG helps to clarify the nature of motor activities of uncertain basis in patients in the intensive care unit and has indicated that non-convulsive seizures or status are more common than clinically suspected in such patients.

Type
Research Article
Copyright
Copyright © Canadian Neurological Sciences Federation 1998

References

REFERENCES

1.Aminoff, MJ, Simon, RP. Status epilepticus: causes, clinical features and consequences in 98 patients. Am J Med 1980; 69: 657666.CrossRefGoogle ScholarPubMed
2.Lowenstein, DH, Aminoff, MJ, Simon, RP. Barbiturate anesthesia in the treatment of status epilepticus: clinical experience with 14 patients. Neurology 1988; 38: 395400.CrossRefGoogle ScholarPubMed
3.Parent, JM, Lowenstein, DH. Treatment of refractory generalized status epilepticus with continuous infusion of midazolam. Neurology 1994; 44: 18371840.CrossRefGoogle ScholarPubMed
4.Yaffe, K, Lowenstein, DH. Prognostic factors of pentobarbital therapy for refractory generalized status epilepticus. Neurology 1993; 43: 895900.CrossRefGoogle ScholarPubMed
5.Simon, RP, Aminoff, MJ. Electrographic status epilepticus in fatal anoxic coma. Ann Neurol 1986; 20: 351355.CrossRefGoogle ScholarPubMed
6.Lowenstein, DH, Aminoff, MJ. Clinical and EEG features of status epilepticus in comatose patients. Neurology 1992; 42: 100104.CrossRefGoogle ScholarPubMed
7.Jordan, KG. Status epilepticus. A perspective from the neuroscience intensive care unit. Neurosurg Clin N Am 1994; 5: 671686.CrossRefGoogle ScholarPubMed
8.Young, GB, Jordan, KG, Doig, GS. An assessment of nonconvulsive seizures in the intensive care unit using continuous EEG monitoring: an investigation of variables associated with mortality. Neurology 1996; 47: 8389.CrossRefGoogle ScholarPubMed