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Lumbo-Sacral Radiculopathy Induced by Radiation

Published online by Cambridge University Press:  18 September 2015

E. M. Ashenhurst ,
G. R. C. Quartey  and
A. Starreveld
E. M. Ashenhurst*
Affiliation:
Division of Neurology, University of Saskatchewan and University Hospital, Saskatoon
G. R. C. Quartey
Affiliation:
Division of Neurology, University of Saskatchewan and University Hospital, Saskatoon
A. Starreveld
Affiliation:
Division of Neurology, University of Saskatchewan and University Hospital, Saskatoon
*
Division of Neurology, University Hospital, Saskatoon, Saskatchewan S7N 0W8
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Two patients had lumbosacral radiculopathy following radiation treatment of cancer. Twenty previously reported cases were similar. The clinical picture is one of progressive motor and sensory loss in the legs, usually appearing within a year after radiation, but sometimes delayed up to several years. Experimental studies quoted indicate greater vulnerability of peripheral nerves to ionizing radiation than has been previously recognized. Lumbo-sacral radiculopathy is readily produced in the experimental animal (rat) and affords an experimental model closely resembling the human cases reported.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 4 , Issue 4 , November 1977 , pp. 259 - 263
Copyright
Copyright © Canadian Neurological Sciences Federation 1977

References

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