Hostname: page-component-586b7cd67f-t8hqh Total loading time: 0 Render date: 2024-11-25T06:54:40.468Z Has data issue: false hasContentIssue false

Julius Caesar's Late Onset Epilepsy: A Case of Historic Proportions

Published online by Cambridge University Press:  02 December 2014

Richard S. McLachlan*
Affiliation:
Department of Clinical Neurological Sciences, University of Western Ontario, London, Ontario, Canada
*
London Health Sciences Centre, 339 Windermere Rd, London, Ontario, N6A 5A5, Canada.
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

This is a case report of Julius Caesar's epilepsy that onset when he was 54-years-old. The differential diagnosis of late onset epilepsy is discussed and the rationale presented for concluding from the clinical presentation that the cause was neurocysticercosis. That this man's disease and its consequences altered the course of history is a very real possibility.

Résumé:

RÉSUMÉ:

Il s’agit d’une analyse de l’histoire d’épilepsie rapportée chez Jules César, dont la maladie aurait débuté alors qu’il avait 54 ans. Nous discutons du diagnostic différentiel de l’épilepsie à début tardif et des raisons qui motivent notre conclusion. À notre avis, il s’agissait d’une neurocysticercose à cause des manifestations cliniques qu’il a présentées. Il est fort possible que la maladie de cet homme et ses conséquences aient modifié le cours de l’histoire.

Type
Historical Review
Copyright
Copyright © The Canadian Journal of Neurological 2010

References

1. Wiebe, S, Bellhouse, DR, Fallahay, C, Eliasziw, M. Burden of epilepsy: the Ontario Health Survey. Can J Neurol Sci. 1999;26:26370.Google Scholar
2. Carr, RH. Plutarch’s life of Julius Caesar in North’s translation. Oxford: Clarendon Press; 1908.Google Scholar
3. Suetonius, GV. (English translation by Rolfe JC). Cambridge MA, London: Wm Heinemann Ltd / Harvard University Press; 1964.Google Scholar
4. Lennox, WG. Epilepsy and related disorders. Vol 2. Boston: Little, Brown and Co; 1960. p. 707.Google Scholar
5. Cawthorne, T. Julius Caesar and the falling sickness. Laryngoscope. 1958;68:144250.Google Scholar
6. Hughes, JR. Dictator Perpetuus: Julius Caesar-did he have seizures? If so, what was the etiology? Epilepsy Behav. 2004;5:75664.CrossRefGoogle ScholarPubMed
7. Ehrenstein, V, Pedersen, L, Holsteen, V, Larsen, H, Rothman, KJ, Sørensen, HT. Postterm delivery and risk for epilepsy in childhood. Pediatrics. 2007;119:55461.Google Scholar
8. Gomez, JG, Kotler, JA, Long, JB. Was Julius Caesar’s epilepsy due to a brain tumor? J Fla Med Assoc. 1995;82:199201.Google Scholar
9. Lieu, AS, Howng, SL. Intracranial meningiomas and epilepsy: incidence, prognosis and influencing factors. Epilepsy Res. 2000;38:4552.Google Scholar
10. Jackson, HJ. Cases of epilepsy associated with syphilis. Med Times Gaz. 1861;1:64858.Google Scholar
11. Sinha, S, Harish, T, Taly, AB, Murthy, P, Nagarathna, S, Chandramuki, A. Symptomatic seizures in neurosyphilis: an experience from a university hospital in south India. Seizure. 2008;17:7116.Google Scholar
12. Kanner, AM. Depression and epilepsy: a review of multiple facets of their close relation. Neurol Clin. 2009; 27:86580.CrossRefGoogle ScholarPubMed
13. Nash, TE, Del Brutto, OH, Butman, JA, et al. Calcific neurocysticercosis and epileptogenesis. Neurology. 2004;62:19348.CrossRefGoogle ScholarPubMed
14. Aristotle, .The history of animals: Book VIII. 350BC.Google Scholar
15. Bruschi, F, Masetti, M, Locci, MT, et al. Short report: cysticercosis in an Egyptian mummy of the late ptolemaic period. Am J Trop Med Hyg. 2006;74:5989.CrossRefGoogle Scholar
16. Del Brutto, OH, Sotello, J, Roman, GC. Neurocysticercosis: a clinical handbook. Lisse: Swets and Zeitlinger; 1998.Google Scholar