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Invited Review: Clinical and Basic Neurophysiology of Generalised Epilepsies

Published online by Cambridge University Press:  02 December 2014

Warren T. Blume
Warren T. Blume*
Affiliation:
London Health Sciences Centre - University Campus, Epilepsy Unit, University of Western Ontario, London, Ontario, Canada
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Abstract

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Electroencephalography (EEG) clarifies several aspects of generalised epileptic seizures and epilepsies. For the clinician, it assists in the diagnosis of the epileptic condition and helps assign the disorder to an appropriate syndrome. This assignation and the quantity of epileptic discharges estimate severity and prognosis. When combined with relevant basic science investigations, EEG studies may disclose significant pathophysiological mechanisms. Therefore, this paper first describes EEG characteristics of the several disorders included under the broad category of “generalised”. The review then relates these phenomena to germane experimental data intending that this binocular survey will provide a more meaningful perspective of these disorders.

Résumé:

RÉSUMÉ:

L'électroencéphalographie éclaire plusieurs aspects des crises épileptiques généralisées et des épilepsies, guide le clinicien pour le diagnostic de la maladie épileptique et l'aide à assigner le désordre au syndrome approprié. Il est possible de déterminer la sévérité et le pronostic selon le syndrome et la quantité de décharges épileptiques. Quand cette information est associée aux investigations fondamentales pertinentes, les études ÉEG peuvent révéler des mécanismes physiopathologiques significatifs. Cet article décrit donc en premier lieu les caractéristiques ÉEG de plusieurs entités comprises sous la catégorie “généralisée”. Une relation est ensuite établie entre ces phénomènes et des données expérimentales pertinentes afin que cette double perspective puisse fournir une perspective plus juste de ces désordres.

Type
Review Article
Information
Canadian Journal of Neurological Sciences , Volume 29 , Issue 1 , February 2002 , pp. 6 - 18
Copyright
Copyright © Canadian Neurological Sciences Federation 2002

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