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Immunohistochemical Study of Foci of Recent Cell Death in Huntington's Disease

Published online by Cambridge University Press:  18 September 2015

P. Averback
P. Averback*
Affiliation:
Department of Pathology, University of Cambridge
*
Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge, England CB2 1QP
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Foci of recent cell death were identified in 10 consecutive cases of Huntington's disease in the caudate nucleus and putamen. Indirect immunohistochemical staining procedures were performed on these areas and controls using fluorescein conjugated anti-globulin and peroxidase-conjugated anti-globulin. Positive results were found when human antiserum to Cytomegalovirus was used. The possibility of abnormal antigen presence within the dying neurons in this disease is discussed.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 7 , Issue 2 , May 1980 , pp. 87 - 88
Copyright
Copyright © Canadian Neurological Sciences Federation 1980

References

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