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Idiopathic Parkinson's disease: Revised Concepts of Cognitive and Affective Status

Published online by Cambridge University Press:  18 September 2015

Ann E. Taylor ,
J.A. Saint-Cyr  and
A.E. Lang
Ann E. Taylor*
Affiliation:
Department of Psychology, Division of Neurology, Toronto Western Hospital, Toronto
J.A. Saint-Cyr
Affiliation:
Playfair Neuroscience Unit, Departments of Anatomy and Psychology, University of Toronto, Division of Neurology, Toronto Western Hospital, Toronto Department of Psychology, Division of Neurology, Toronto Western Hospital, Toronto
A.E. Lang
Affiliation:
Department of Medicine, University of Toronto, Division of Neurology, Toronto Western Hospital, Toronto Department of Medicine, Division of Neurology, Toronto Western Hospital, Toronto
*
Department of Psychology, Toronto Western Hospital, 399 Bathurst Street, Toronto, Ontario, Canada M5T 2S8
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Abstract:

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Assumptions regarding increased risk of dementia in Parkinson's disease and of depression mimicking the endogenous form are reviewed and challenged from the perspectives of recent findings in both the neuropsychological and anatomical domains. Evidence suggests that depression, while frequent, behaviourally resembles the reactive variety and that selective impairment of cognitive functions considered to depend upon the integrity of the frontal lobes accompanies this disorder. In this regard, it is speculated that the cognitive alterations seen in non-demented parkinson patients are the consequences of dysfunction of the caudate nucleus which contributes significantly to the normal activities processed through the frontostriate “complex loop”.

Type
Special Features
Information
Canadian Journal of Neurological Sciences , Volume 15 , Issue 2 , May 1988 , pp. 106 - 113
Copyright
Copyright © Canadian Neurological Sciences Federation 1988

References

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