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Heterotopic Growth of Dysplastic Cerebellum in Frontal Encephalocele in an Infant of a Diabetic Mother

Published online by Cambridge University Press:  18 September 2015

Harvey B. Sarnat ,
Daphne E. deMello ,
John D. Blair  and
Saeeda Y. Siddiqui
Harvey B. Sarnat*
Affiliation:
Departments of Paediatrics (Neurology) and Pathology, University of Calgary Faculty of Medicine, Calgary, Alberta and the Department of Pathology, Saint Louis University School of Medicine, St. Louis, Missouri, USA
Daphne E. deMello
Affiliation:
Departments of Paediatrics (Neurology) and Pathology, University of Calgary Faculty of Medicine, Calgary, Alberta and the Department of Pathology, Saint Louis University School of Medicine, St. Louis, Missouri, USA
John D. Blair
Affiliation:
Departments of Paediatrics (Neurology) and Pathology, University of Calgary Faculty of Medicine, Calgary, Alberta and the Department of Pathology, Saint Louis University School of Medicine, St. Louis, Missouri, USA
Saeeda Y. Siddiqui
Affiliation:
Departments of Paediatrics (Neurology) and Pathology, University of Calgary Faculty of Medicine, Calgary, Alberta and the Department of Pathology, Saint Louis University School of Medicine, St. Louis, Missouri, USA
*
University of Calgary Faculty of Medicine, Alberta Children’s Hospital, 1820 Richmond Road, S.W., Calgary, Alberta, T2T 5C7
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Summary:

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An infant of a diabetic mother lived 13 days after birth. She had a small dysplastic 12.6 gm. brain, partly forming a frontal encephalocele. The uncleaved forebrain contained a mass of poorly organized heterotopic cerebellar cortex. The cerebellum itself had normal lamination, but was small and continuous with the dysplastic tissue. The ventricular system was absent except for a few midline ependymal rosettes, and the cerebral cortex was not developed. The cerebellar dysplasia resembled a proliferative and invasive lesion by its rostral extension.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 9 , Issue 1 , February 1982 , pp. 31 - 35
Copyright
Copyright © Canadian Neurological Sciences Federation 1982

References

REFERENCES

Altman, J., Bayer, S.A. (1978). Prenatal development of the cerebellar system in the rat. I. Cytogenesis and histogenesis of the deep nuclei and cortex of the cerebellum. J Comp Neurol, 179: 23–48.CrossRefGoogle ScholarPubMed
Ambler, M., Pogacar, S., Sidman, R. (1969). Lhermitte-Duclos disease (granule cell hypertrophy of the cerebellum). Pathological analysis of the first familial cases. J. Neuropatl ol Exp Neurol, 28: 622–647.Google ScholarPubMed
Christensen, E. (1937). Über Ganglienzellgeschwülste im Gehirn. Virchows Arch Path Anat, 300: 567–581.CrossRefGoogle Scholar
Courville, C.B. (1958). Gangliocytoma myelinicum of the cerebellar cortex. Bull Los Angeles Neurol Soc, 23: 72–80.Google ScholarPubMed
Das, G.D., Nornes, H.O. (1972). Neurogenesis in the cerebellum of the rat: An autoradiographic study. Z Anat Entwickl-Gesch, 138: 155–165.CrossRefGoogle ScholarPubMed
Dekaban, A.S., Magee, K.R. (1958). Occurrence of neurologic abnormalities in infants of diabetic mothers. Neurology, 8: 193–200.CrossRefGoogle ScholarPubMed
Donat, J.F.G. (1981). Septo-optic dysplasia in an infant of a diabetic mother. Arch Neurol, 38: 590–591.CrossRefGoogle Scholar
Duncan, D., Snodgrass, S.R. (1943). Diffuse hypertrophy of the cerebellar cortex (myelinated neurocytoma). Arch Neurol Psychiat, 50: 677–684.CrossRefGoogle Scholar
Foerster, O., Gagel, O. (1933). Ein Fall von Gangliocytoma dysplasticum des Kleinhirns. Ztschr f d ges Neurol u Psychiat, 146: 792–803.CrossRefGoogle Scholar
Friede, R.L. (1975). Developmental Neuropathology. Springer-Verlag, NY, Vienna, pp 236–239, 326–338.CrossRefGoogle Scholar
Friede, R.L., Yasargil, M.G. (1977). Suprasellar neoplasm with a granular cell component. J Neuropathol Exp Neurol, 36: 769–782.CrossRefGoogle ScholarPubMed
Hallervorden, J. (1959). Über die Hamartome (Ganglioneurome) des Kleinhirns. Dtsch Ztschr Nervenhk, 179: 531–563.Google Scholar
Karch, S.B., Urich, H. (1972). Occipital encephalocele: A morphologic study. J Neurol Sci, 15: 89–112.CrossRefGoogle Scholar
Lhermitte, J., Duclos, P. (1920). Sur un ganglioneuroma diffus du cortex du cervelet. Bull Assoc Franc Cancer, 9: 99–107.Google Scholar
Masters, C.L. (1978). Pathogenesis of encephalocele and anencephaly: Relationship to the ventricular system and the significance of hydrocephalus. J Neuropathol Exp Neurol, 37: 656.CrossRefGoogle Scholar
Netsky, M.G., Shuangshoti, S. (1975). The Choroid Plexus in Health and Disease. Univ. Press of Virginia, Charlottesville.Google Scholar
Oppenheimer, D.R. (1955). A benign. “tumor” of the cerebellum. Report on two cases of diffuse hypertrophy of the cerebellar cortex with a review of nine previously reported cases. J Neurol Neurosurg Psychiat, 18: 199–213.CrossRefGoogle Scholar
Pritchett, P.S., King, T.I. (1978). Dysplastic gangliocytoma of the cerebellum. An ultrastructural study. Acta Neuropathol, 42: 1–5.CrossRefGoogle ScholarPubMed
Simeoni, S. (1966). Il gangliocitoma displastico del cervelleto. Giorn ltal di Patologia e Scienze Affini, 13: 1–46.Google Scholar