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Glutamate and Aspartate Do Not Modify the Ataxic Gait of Acrylamide Treated Animals

Published online by Cambridge University Press:  18 September 2015

G. De Michele ,
F.B. Jolicoeur  and
A. Barbeau
G. De Michele
Affiliation:
Department of Neurobiology, Clinical Research Institute of Montreal
F.B. Jolicoeur
Affiliation:
Department of Neurobiology, Clinical Research Institute of Montreal
A. Barbeau*
Affiliation:
Department of Neurobiology, Clinical Research Institute of Montreal
*
Clinical Research Institute of Montreal, 110 Pine Avenue West, Montréal, Quebec, Canada H2W 1R7
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Summary:

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The purpose of this experiment was to examine the effects of intraventricular injections of glutamate and aspartate on the gait of animals rendered ataxic by the administration of acrylamide. Contrary to their previously reported corrective Influence on ataxia induced by 3-acetyl pyridine, these amino acids did not modify the ataxic gait of acrylamide treated animals. This suggests that glutamate and aspartate can act in cerebellar but not in peripheral types of ataxia in animals.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 9 , Issue 2 , May 1982 , pp. 179 - 180
Copyright
Copyright © Canadian Neurological Sciences Federation 1982

References

REFERENCES

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