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Friedreich's Ataxia in the South of Italy : A Clinical and Biochemical Survey of 23 Patients

Published online by Cambridge University Press:  18 September 2015

G. Campanella ,
A. Filla ,
F. De Falco ,
D. Mansi ,
A. Durivage  and
A. Barbeau
G. Campanella
Affiliation:
Department of Neurology, Second School of Medicine, University of Naples (Italy) and Department of Neurobiology, Clinical Research Institute of Montreal
A. Filla
Affiliation:
Department of Neurology, Second School of Medicine, University of Naples (Italy) and Department of Neurobiology, Clinical Research Institute of Montreal
F. De Falco
Affiliation:
Department of Neurology, Second School of Medicine, University of Naples (Italy) and Department of Neurobiology, Clinical Research Institute of Montreal
D. Mansi
Affiliation:
Department of Neurology, Second School of Medicine, University of Naples (Italy) and Department of Neurobiology, Clinical Research Institute of Montreal
A. Durivage
Affiliation:
Department of Neurology, Second School of Medicine, University of Naples (Italy) and Department of Neurobiology, Clinical Research Institute of Montreal
A. Barbeau*
Affiliation:
Department of Neurology, Second School of Medicine, University of Naples (Italy) and Department of Neurobiology, Clinical Research Institute of Montreal
*
Clinical Research Institute of Montreal, 110 Pine Avenue West, Montreal, Quebec, Canada, H2W 1R7
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We report a clinical and biochemical survey of 23 patients with Friedreich's ataxia from southern Italy. They were studied clinically and by means of a clinical rating scale devised by us (Inherited Ataxias Clinical Rating Scale). Laboratory tests, based on the Quebec Cooperative Study, were also performed on our patients. No major clinical or biochemical differences were found between Italian and Canadian patients. Investigation of CSF monoamine metabolites showed that HVA decreased after probenecid and metoclopramide loading

Type
Quebec Cooperative Study of Friedreich's Ataxia
Information
Canadian Journal of Neurological Sciences , Volume 7 , Issue 4 , November 1980 , pp. 351 - 357
Copyright
Copyright © Canadian Neurological Sciences Federation 1980

References

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