Hostname: page-component-78c5997874-mlc7c Total loading time: 0 Render date: 2024-11-20T05:38:42.969Z Has data issue: false hasContentIssue false
  • English
  • Français

Extramedullary Hematopoiesis Simulating Parasagittal Meningioma

Published online by Cambridge University Press:  18 September 2015

R.A. Kandel ,
K.P.H. Pritzker ,
A.S. Gordon  and
J.M. Bilbao
R.A. Kandel
Affiliation:
Departments of Pathology and Medicine, Mount Sinai Hospital and the University of Toronto, Toronto Canada
K.P.H. Pritzker*
Affiliation:
Departments of Pathology and Medicine, Mount Sinai Hospital and the University of Toronto, Toronto Canada
A.S. Gordon
Affiliation:
Departments of Pathology and Medicine, Mount Sinai Hospital and the University of Toronto, Toronto Canada
J.M. Bilbao
Affiliation:
Departments of Pathology and Medicine, Mount Sinai Hospital and the University of Toronto, Toronto Canada
*
Department of Pathology, Mount Sinai Hospital, 600 University Avenue, Toronto, Canada, M5G 1X5
Rights & Permissions [Opens in a new window]

Abstract:

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

We report a patient with polycythemia vera and myeloid metaplasia of nine years duration who developed raised intracranial pressure related to a mass obliterating the sagittal fissure. Although clinically and radiologically simulating a meningioma, biopsy revealed extramedullary hematopoiesis involving the falx cerebri. Although uncommon, this case illustrates that myeloproliferative disease can present with symptomatology and radiologic features similar to primary intracranial tumours.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 9 , Issue 1 , February 1982 , pp. 49 - 51
Copyright
Copyright © Canadian Neurological Sciences Federation 1982

References

REFERENCES

Clinical Pathologic Conference. Myelofibrosis with unusual neurologic abnormalities. AACH Richard Kissane, John, (editor) (1971). Am J Med, 51: 799–811.Google Scholar
Adamson, J.W., Fialkow, P.J., Murphy, S., Prchal, J.F., Steinmann, L. (1976) Polycythemia vera: stem cell and probable clonal origin of the disease NEJM, 295: 913.Google Scholar
Adamson, J.W. and Fialkow, P.J. (1978). The pathogenesis of myeloproliferative syndromes. Br J Hematology, 38: 299–303.CrossRefGoogle ScholarPubMed
Barr, R.D. and Fialkow, P.J. (1973). Clonal origin of CML. NEJM, 289: 307–309.CrossRefGoogle Scholar
Brannon, D. (1927). Extramedullar hematopoiesis in anemias. Bull John Hopkins Hospital, 41: 104–136.Google Scholar
Damshek, W. (1951). Some speculations on the myeloproliferative syndromes. Blood, 6: 372–375.CrossRefGoogle Scholar
Glew, R.H., Haese, W.H., McIntyre, P.A. (1973). Myeloid metaplasia with myelofibrosis. The clincial spectrum of EMH and tumour formation. Hopkins Med J, 132: 253–270.Google ScholarPubMed
Hu, C.H. and Cash, J.R. (1930). Erosion of the inner table of the skull by hyperplasia of bone marrow in Kala Azar with extramedullary formation of blood on the surface of the dura. Trans 7th Congress Far East Assoc Trop Med 1927,3: 80–84.Google Scholar
Korpassay, B., and Kelemen, E. (1949). Vaquez-Osler’sche Krankheit-Panmyelose. Acta Hematol, 2: 110–124.CrossRefGoogle Scholar
Lieberman, R.H., Rosvoll, R.V.Ley, A.B. (1965). Extramedullar myeloid tumours in primary myelofibrosis. Cancer, 18: 727–736.3.0.CO;2-8>CrossRefGoogle Scholar
Ligumski, M., Polliack, A., Benbassat, J. (1978). Myeloid metaplasia of the central nervous system in patients with myelofibrosis and agnogenic myeloid metaplasia. Am J Med Sci, 275: 99–103.CrossRefGoogle ScholarPubMed
Polliack, A., and Rosenmann, E. (1969). Extramedullar hematopoietic tumours of the cranial dura mater. Acta Haematol, 41: 43–48.CrossRefGoogle Scholar
Rutman, J.Y., Meidinger, R., Keith, J.I. (1972). Unusual radiological and neurologic findings in a case of myelofibrosis with EMH. Neurology, 22: 567–570.Google Scholar
Vegh, P., and Jankovies, R. (1964). Uber Eine Erkrankung an myelosklerosc mit seltenem Verlauf nach Milzent Fernung. Folia Haematologica, 83: 16–25.Google Scholar
Ward, H.P., and Block, M.H. (1971). The natural history of AMM and a critical evaluation of its relationship with the myeloproliferative syndrome. Medicine, 50: 357–420.CrossRefGoogle Scholar