Background: Spinal infections are one of the most difficult, complex, and multi-disciplinary health conditions. The purpose of this paper was to gather demographic information of the patients with spinal infections and to identify factors that would influence their management. Methods: Retrospective chart review of 146 adult patients with osteomyelitis, discitis or epidural abscesses admitted to the Royal University Hospital, Saskatchewan, from 2007-2014. Results: Patient demographics included 59% male, 41% female, mean age 53 years. 36% of patients required surgery, 44% were IV drug users, and 71% were managed by surgeons. Presence of a neurological deficit, higher white blood cell count, and longer hospital admission, in relation to poor outcomes, were statistically significant. Higher age and shorter duration between onset of symptoms and admission showed a trend toward a poorer outcome. Epidural abscess and presence of a neurological deficit are variables isolated as being statistically significant in relation to need for surgery. 57.1% of patients with epidural abscess and 51.7% with neurological deficit required surgery. Conclusions: We were able to identify high-risk patients as to the need for surgery and poor outcome. Based on this information, we can better tailor our management strategy of this difficult condition.