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Dietary Folic Acid and The Activity of Brain Cholinergic and γ-Aminobutyric Acid (GABA) Enzymes

Published online by Cambridge University Press:  18 September 2015

M.I. Botez ,
Jocelyne Bachevalier  and
G. Tunnicliff
M.I. Botez*
Affiliation:
Clinical Research Institute of Montreal and Hôtel-Dieu Hospital, Montreal, P.Q., Canada
Jocelyne Bachevalier
Affiliation:
Clinical Research Institute of Montreal and Hôtel-Dieu Hospital, Montreal, P.Q., Canada
G. Tunnicliff
Affiliation:
Clinical Research Institute of Montreal and Hôtel-Dieu Hospital, Montreal, P.Q., Canada
*
110 Pine Ave, West, Montreal, Quebec H2W 1R7, Canada
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Charles River CD male rats were randomly divided into 3 groups of five each and placed on folate deficient, folate excess, and control diets respectively. Glutamate decarboxylase GA D y-aminohutyrate aminotransferase (GABA-T), choline acetyltransferase (ChAc), and acetylcholinesterase (AChE) were assayed in the rat brains after 6 weeks of dietary treatment. Neither folate deficiency nor folate supplementation influenced the enzymes associated with GABA and acetylcholine metabolism.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 7 , Issue 2 , May 1980 , pp. 133 - 134
Copyright
Copyright © Canadian Neurological Sciences Federation 1980

References

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