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Cytoplasmic Tubular Aggregates and Nuclear Filamentous Bodies in Two Suspected Cases of Viral Encephalitis

Published online by Cambridge University Press:  18 September 2015

Dikran S. Horoupian ,
R.T. Ross ,
Mark J. Gurwith  and
Jan Hoogstraten
Dikran S. Horoupian*
Affiliation:
Department of Pathology and Medicine Health Sciences Centre and Faculty of Medicine, University of Manitoba, Winnipeg, Canada
R.T. Ross
Affiliation:
Department of Pathology and Medicine Health Sciences Centre and Faculty of Medicine, University of Manitoba, Winnipeg, Canada
Mark J. Gurwith
Affiliation:
Department of Pathology and Medicine Health Sciences Centre and Faculty of Medicine, University of Manitoba, Winnipeg, Canada
Jan Hoogstraten
Affiliation:
Department of Pathology and Medicine Health Sciences Centre and Faculty of Medicine, University of Manitoba, Winnipeg, Canada
*
Neuropathology Unit, Department of Pathology, Health Sciences Centre, 700 William Avenue, Winnipeg, Manitoba R3E 0Z3 Canada
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Summary

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Two suspected cases of viral encephalitis are presented. Viral nucleocapsids were not seen, but cytoplasmic paramyxovirus-like aggregates and nuclear filamentous bodies were frequently encountered. Both structures were seen in the same cell. Contrary to other reports, the cytoplasmic aggregates were mostly observed in hematogenous mononuclear cells, less frequently in neuronal cell elements and rarely in endothelial cells. The non-specific nature of these structures is emphasized.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 1 , Issue 2 , May 1974 , pp. 98 - 105
Copyright
Copyright © Canadian Neurological Sciences Federation 1974

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