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Cucumber Shaped and 35 nm Particles in Creutzfeldt-Jakob Disease

Published online by Cambridge University Press:  18 September 2015

Dikran S. Horoupian  and
R.T. Ross
Dikran S. Horoupian*
Affiliation:
Departments of Pathology and Medicine, Health Sciences Center and Faculty of Medicine, University of Manitoba, Winnipeg, Canada
R.T. Ross
Affiliation:
Departments of Pathology and Medicine, Health Sciences Center and Faculty of Medicine, University of Manitoba, Winnipeg, Canada
*
Department of Pathology, Henry Ford Hospital, 2799 West Grand Blvd., Detroit, Michigan 48202 U.S.A.
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Summary:

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A 63 year old female with the ataxic form of Creutzfeldt-Jakob disease (CJD) is presented. In addition to amyloid plaques which were not associated with Alzheimer’s neurofibrillary tangles, rare profiles similar to those reported in Scrapie were also seen. To our knowledge, these profiles have never been observed in CJD and their presence in this condition adds a further morphologic similarity between the human and animal forms of subacute spongiform “viral” encephalopathies.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 2 , Issue 3 , August 1975 , pp. 203 - 207
Copyright
Copyright © Canadian Neurological Sciences Federation 1975

References

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