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Cross Correlation Studies in Primate Motor Cortex: Event Related Correlation

Published online by Cambridge University Press:  18 September 2015

John T. Murphy ,
Hon C. Kwan  and
Yiu C. Wong
John T. Murphy*
Affiliation:
Departments of Physiology and Medicine, University of Toronto
Hon C. Kwan*
Affiliation:
Departments of Physiology and Medicine, University of Toronto
Yiu C. Wong*
Affiliation:
Departments of Physiology and Medicine, University of Toronto
*
11–241 Eaton North, Toronto General Hospital. 101 College Street, Toronto, Ontario, Canada M5G 1L7
11–241 Eaton North, Toronto General Hospital. 101 College Street, Toronto, Ontario, Canada M5G 1L7
11–241 Eaton North, Toronto General Hospital. 101 College Street, Toronto, Ontario, Canada M5G 1L7
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Abstract:

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Simultaneous extracellular unit recordings were made from each cell of 237 pairs in two awake monkeys, during a voluntary reaching movement of the forelimb. The cells were located in contralateral precentral cortex and functionally coupled to single forelimb joints, as indicated by intracortical microstimulation and passive sensory stimulation. Cross correlation analysis showed that 72 of these pairs exhibited significant event-related correlation over periods of up to 780 ms, comparable to and coincident with the forelimb movement. Spatial analysis showed that such correlation extended across contiguous portions of all four forelimb joint zones of precentral cortex, over distances up to 3.5 mm. No preferred direction of correlation was observed. The data confirm the previously described nested organization of the forelimb area of precentral cortex. Findings are discussed in terms of mechanisms by which columns of neurons in motor cortex participate in the reaching movement.

Type
Articles
Information
Canadian Journal of Neurological Sciences , Volume 12 , Issue 1 , February 1985 , pp. 24 - 30
Copyright
Copyright © Canadian Neurological Sciences Federation 1985

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