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Correlation of CT and MR with Impedance Monitoring and Histopathology in Stereotactic Biopsies

Published online by Cambridge University Press:  18 September 2015

J. Gorecki ,
E.J. Dolan ,
R.R. Tasker  and
W. Kucharczyk
J. Gorecki
Affiliation:
Division of Neurosurgery and Department of Radiology, Toronto General Hospital and University of Toronto, Toronto
E.J. Dolan*
Affiliation:
Division of Neurosurgery and Department of Radiology, Toronto General Hospital and University of Toronto, Toronto
R.R. Tasker
Affiliation:
Division of Neurosurgery and Department of Radiology, Toronto General Hospital and University of Toronto, Toronto
W. Kucharczyk
Affiliation:
Division of Neurosurgery and Department of Radiology, Toronto General Hospital and University of Toronto, Toronto
*
Division of Neurosurgery, Toronto General Hospital, Room 222, 14 Eaton North, 200 Elizabeth Street, Toronto, Ontario, Canada M5G 2C4
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Abstract:

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Magnetic Resonance Imaging (MR) and Computer Assisted Tomography (CT) guided stereotaxis combined with intraoperative impedance monitoring and multiple sequential biopsies provides the opportunity to correlate the results of radiologic imaging with impedance and histopathology. The authors present the methods used and preliminary results obtained from 30 stereotactic biopsies with complete correlation in 12 cases. Impedance changes correlate accurately with lesion margins as defined by histology. CT images of enhancing lesions correlate quite closely to the histopathologic lesion margins whereas the appearance of the lesion on MR images is often larger than subsequently identified by either impedance or at pathologic examination. Impedance monitoring is a useful adjunct to stereotactic biopsy as it helps to accurately define lesion margins and can help direct the choice of biopsy sites.

Résumé:

RÉSUMÉ:

La stéréotaxie guidée au moyen de l'imagerie par résonance magnétique (MR) et de la tomographie assistée par ordinateur (CT) combinée au monitoring de l'impédance peropératoire et à des biopsies séquentielles multiples fournissent l'occasion de corréler les résultats de l'imagerie radiologique avec ceux de l'impédance et de l'histopathologie. Les auteurs présentent les méthodes utilisées et les résultats préliminaires obtenus à partir de 30 biopsies prélevées sous stéréotaxie avec corrélation complète dans 12 cas. Les changements d'impédance ont une corrélation précise avec les limites de la lésion telles que définies par l'examen histologique. Il y a une corrélation assez étroite entre les images par CT de lésions qui rehaussent au produit de contraste et les limites histopathologiques de ces lésions, alors que les images par MR montrent souvent des lésions plus étendues que ce qui est constaté ultérieurement lors de l'examen par impédance ou à la pathologie. Le monitoring par impédance est un complément utile à la biopsie stéréotaxique parce qu'il aide à définir précisément les limites des lésions et peut aider à choisir les sites de biopsie.

Type
Neurosurgical Symposium - William S. Keith, Visiting Professorship in Neurosurgery
Information
Canadian Journal of Neurological Sciences , Volume 17 , Issue 2 , May 1990 , pp. 184 - 189
Copyright
Copyright © Canadian Neurological Sciences Federation 1990

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